Childhood socio-economic status (SES), a measure of the availability of material and social
resources, is one of the strongest predictors of lifelong well-being. Here we review evidence …

The cumulative science linking stress to negative health outcomes is vast. Stress can affect
health directly, through autonomic and neuroendocrine responses, but also indirectly …

Introduction: Allostatic load refers to the cumulative burden of chronic stress and life events.
It involves the interaction of different physiological systems at varying degrees of activity …

Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

The high prevalence and psychological impact of childhood exposure to potentially
traumatic events (PTE) is a major public health concern in the United States. Considerable …

Background An increasing number of studies are identifying associations between adverse
childhood experiences (ACEs) and ill health throughout the life course. We aimed to …

Is the field of cognitive aging irretrievably concerned with decline and deficits, or is it shifting
to emphasize the hope of preservation and enhancement of cognitive function in late life? A …

Does psychopathology develop as a function of the objective or subjective experience of
childhood maltreatment? To address this question, we studied a unique cohort of 1,196 …