[HTML][HTML] Drug repurposing for COVID-19 via knowledge graph completion

R Zhang, D Hristovski, D Schutte, A Kastrin… - Journal of biomedical …, 2021 - Elsevier
Objective To discover candidate drugs to repurpose for COVID-19 using literature-derived
knowledge and knowledge graph completion methods. Methods We propose a novel …

[PDF][PDF] Contexts and contradictions: a roadmap for computational drug repurposing with knowledge inference

DN Sosa, RB Altman - Briefings in Bioinformatics, 2022 - academic.oup.com
The cost of drug development continues to rise and may be prohibitive in cases of unmet
clinical need, particularly for rare diseases. Artificial intelligence-based methods are …

Review of Natural Language Processing in Pharmacology

D Trajanov, V Trajkovski, M Dimitrieva, J Dobreva… - Pharmacological …, 2023 - ASPET
Natural language processing (NLP) is an area of artificial intelligence that applies
information technologies to process the human language, understand it to a certain degree …

Knowledge4COVID-19: A semantic-based approach for constructing a COVID-19 related knowledge graph from various sources and analyzing treatments' toxicities

A Sakor, S Jozashoori, E Niazmand, A Rivas… - Journal of Web …, 2023 - Elsevier
In this paper, we present Knowledge4COVID-19, a framework that aims to showcase the
power of integrating disparate sources of knowledge to discover adverse drug effects …

[HTML][HTML] Causal knowledge graph construction and evaluation for clinical decision support of diabetic nephropathy

K Lyu, Y Tian, Y Shang, T Zhou, Z Yang, Q Liu… - Journal of Biomedical …, 2023 - Elsevier
Background Many important clinical decisions require causal knowledge (CK) to take action.
Although many causal knowledge bases for medicine have been constructed, a …

PubTator 3.0: an AI-powered literature resource for unlocking biomedical knowledge

CH Wei, A Allot, PT Lai, R Leaman, S Tian… - Nucleic Acids …, 2024 - academic.oup.com
Abstract PubTator 3.0 (https://www. ncbi. nlm. nih. gov/research/pubtator3/) is a biomedical
literature resource using state-of-the-art AI techniques to offer semantic and relation …

OpCitance: Citation contexts identified from the PubMed Central open access articles

TK Hsiao, VI Torvik - Scientific Data, 2023 - nature.com
OpCitance contains all the sentences from 2 million PubMed Central open-access (PMCOA)
articles, with 137 million inline citations annotated (ie, the “citation contexts”). Parsing out the …

[HTML][HTML] The precision medicine process for treating rare disease using the artificial intelligence tool mediKanren

A Foksinska, CM Crowder, AB Crouse… - Frontiers in Artificial …, 2022 - frontiersin.org
There are over 6,000 different rare diseases estimated to impact 300 million people
worldwide. As genetic testing becomes more common practice in the clinical setting, the …

KGML-xDTD: a knowledge graph–based machine learning framework for drug treatment prediction and mechanism description

C Ma, Z Zhou, H Liu, D Koslicki - GigaScience, 2023 - academic.oup.com
Background Computational drug repurposing is a cost-and time-efficient approach that aims
to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It …

Pandemic tele-smart: a contactless tele-health system for efficient monitoring of remotely located COVID-19 quarantine wards in India using near-field communication …

V Balasubramanian, S Vivekanandhan… - Medical & biological …, 2022 - Springer
Efficient remote monitoring of the patient infected with coronavirus without spread to
healthcare workers is the need of the hour. An effectual and faster communication system …