Regulatory pathways and drugs associated with ferroptosis in tumors

D Wang, L Tang, Y Zhang, G Ge, X Jiang, Y Mo… - Cell Death & …, 2022 - nature.com
Ferroptosis is a type of cell death that depends on iron and reactive oxygen species (ROS).
The accumulation of iron and lipid peroxidation primarily initiates oxidative membrane …

Ferroptosis: a double-edged sword mediating immune tolerance of cancer

Q Dang, Z Sun, Y Wang, L Wang, Z Liu, X Han - Cell death & disease, 2022 - nature.com
The term ferroptosis was put forward in 2012 and has been researched exponentially over
the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed …

[HTML][HTML] Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases

Y Liu, W Ding, J Wang, X Ao, J Xue - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cardiovascular disease (CVD) is a major contributor to increasing morbidity and mortality
worldwide and seriously threatens human health and life. Cardiomyocyte death is …

[HTML][HTML] BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection

Y Chen, X Yi, B Huo, Y He, X Guo, Z Zhang… - Pharmacological …, 2022 - Elsevier
Smooth muscle cell (SMC) loss is the characteristic feature in the pathogenesis of aortic
dissection (AD), and ferroptosis is a novel iron-dependent regulated cell death driven by the …

[HTML][HTML] Ferroptosis-Related Long Non-Coding RNA signature predicts the prognosis of Head and neck squamous cell carcinoma

Y Tang, C Li, YJ Zhang, ZH Wu - International journal of biological …, 2021 - ncbi.nlm.nih.gov
Background: Head and neck squamous cell carcinoma (HNSCC) are head and neck
cancers. On the other hand, ferroptosis is a novel iron-dependent and ROS reliant type of …

Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop …

Y Luo, S Huang, J Wei, H Zhou, W Wang… - Clinical and …, 2022 - Wiley Online Library
Background Ferroptosis is principally caused by iron catalytic activity and intracellular lipid
peroxidation. Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis …

Role of ferroptosis in lung diseases

W Xu, H Deng, S Hu, Y Zhang, L Zheng… - Journal of …, 2021 - Taylor & Francis
Ferroptosis is a new type of programmed cell death characterized by intracellular iron
accumulation and lipid peroxidation that leads to oxidative stress and cell death. The …

Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells

H Zhang, M Wang, Y He, T Deng, R Liu, W Wang… - Cell Death & …, 2021 - nature.com
Cancer stem cells (CSCs) are an important cause of tumor recurrence and drug resistance.
As a new type of cell death that relies on iron ions and is strictly regulated by intracellular …

Ferroptosis as a mechanism of non-ferrous metal toxicity

M Aschner, AV Skalny, AC Martins, AI Sinitskii… - Archives of …, 2022 - Springer
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …

Ferroptosis-related lncRNA pairs to predict the clinical outcome and molecular characteristics of pancreatic ductal adenocarcinoma

R Tang, Z Wu, Z Rong, J Xu, W Wang… - Briefings in …, 2022 - academic.oup.com
Ferroptosis is a form of regulated cell death initiated by oxidative perturbations that can be
blocked by iron chelators and lipophilic antioxidants, and ferroptosis may be the silver bullet …