[HTML][HTML] An introduction to nanopore sequencing: past, present, and future considerations

M MacKenzie, C Argyropoulos - Micromachines, 2023 - mdpi.com
There has been significant progress made in the field of nanopore biosensor development
and sequencing applications, which address previous limitations that restricted widespread …

[HTML][HTML] Recent advances in forensic biology and forensic DNA typing: INTERPOL review 2019–2022

JM Butler - Forensic Science International: Synergy, 2023 - Elsevier
This review paper covers the forensic-relevant literature in biological sciences from 2019 to
2022 as a part of the 20th INTERPOL International Forensic Science Managers Symposium …

[HTML][HTML] Cas9 targeted nanopore sequencing with enhanced variant calling improves CYP2D6-CYP2D7 hybrid allele genotyping

K Rubben, L Tilleman, K Deserranno, O Tytgat… - PLoS …, 2022 - journals.plos.org
CYP2D6 is a very important pharmacogene as it is responsible for the metabolization or
bioactivation of 20 to 30% of the clinically used drugs. However, despite its relatively small …

Forensic nanopore sequencing of microhaplotype markers using QitanTech's QNome

Z Wang, L Qin, J Liu, L Jiang, X Zou, X Chen… - Forensic Science …, 2022 - Elsevier
In recent years, extraordinary progress has been made in genome sequencing
technologies, which has led to a decrease in cost and an increase in the diversity of …

[HTML][HTML] Variable fragment length allele-specific polymerase chain reaction (VFLASP), a method for simple and reliable genotyping

T Tóth, Á Csaba, A Bokor, N Ács - Molecular and Cellular Probes, 2023 - Elsevier
Single-nucleotide polymorphism (SNP) is a substitution of a single nucleotide at a specific
position in the genome. Until now, 585 million SNPs have been identified in the human …

[HTML][HTML] Classification of Neisseria meningitidis genomes with a bag-of-words approach and machine learning

M Podda, S Bonechi, A Palladino, M Scaramuzzino… - Iscience, 2024 - cell.com
Whole genome sequencing of bacteria is important to enable strain classification. Using
entire genomes as an input to machine learning (ML) models would allow rapid …

[HTML][HTML] STR genotyping by real-time PCR using QueSTR probes

S Škevin, O Tytgat, M Fauvart, L De Keyzer… - Sensors and Actuators B …, 2023 - Elsevier
QueSTR probes provide a feasible alternative for implementing forensic Short Tandem
Repeat (STR) genotyping on lab-on-a-chip (LoC) devices. Unlike capillary electrophoresis …

Forensic DNA phenotyping using Oxford Nanopore Sequencing system

V Sapan, SZ Simsek, G Filoğlu, O Bulbul - Electrophoresis, 2024 - Wiley Online Library
In forensic science, the demand for precision, consistency, and cost‐effectiveness has
driven the exploration of next‐generation sequencing technologies. This study investigates …

Pilot validation of on‐field STR typing and human identity testing by MinION nanopore sequencing

Y Luo, J Zhang, M Ni, Z Mei, Q Ye, B Guo… - …, 2024 - Wiley Online Library
Nanopore sequencing technology has broad application prospects in forensic medicine due
to its small size, portability, fast speed, real‐time result analysis capabilities, single‐molecule …

Validation of the InnoXtract™ DNA extraction method for bone, teeth, and rootless hair

SK Sinha, H Brown, H Holt, M Khan… - Journal of Forensic …, 2023 - Wiley Online Library
Forensic casework samples often include human hairs, teeth, and bones. Hairs with roots
are routinely processed for DNA analysis, while rootless hairs are either not tested or …