Schizophrenia is a severe psychiatric disorder with considerable morbidity and mortality.
Although the past two decades have seen limited improvement in the treatment of …

Bipolar disorder (BD) is a highly heritable mental disorder and is estimated to affect about 50
million people worldwide. Our understanding of the genetic etiology of BD has greatly …

Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

Mendelian-randomization (MR) studies using large-scale genome-wide association studies
(GWAS) have identified causal association between educational attainment and Alzheimer's …

Personality and cognitive function are heritable mental traits whose genetic foundations may
be distributed across interconnected brain functions. Previous studies have typically treated …

The folding of the human cerebral cortex is a highly genetically regulated process that
allows for a much larger surface area to fit into the cranial vault and optimizes functional …

Background Recent genome-wide association studies (GWASs) have revealed the
polygenic nature of psychiatric disorders and discovered a few of single-nucleotide …

Epidemiological and clinical studies have found associations between depression and
cardiovascular disease risk factors, and coronary artery disease patients with depression …

Objective: Schizophrenia is associated with increased risk of cardiovascular disease (CVD),
although there is variation in risk among individuals. There are indications of shared genetic …

The thalamus is a vital communication hub in the center of the brain and consists of distinct
nuclei critical for consciousness and higher-order cortical functions. Structural and functional …