While there is widespread concern regarding the impact of pesticides on honey bees, well-
replicated field experiments, to date, have failed to provide clear insights on pesticide …

Perfect adaptation is a phenomenon whereby the output variables of a system can maintain
certain values despite external disturbances. Robust perfect adaptation (RPA) refers to an …

Despite their complexity, biological systems are able to endure huge parameter fluctuations
and survive in the most diverse environmental conditions. Mathematical tools from graph …

For a vast class of dynamical networks, including chemical reaction networks (CRNs) with
monotonic reaction rates, the existence of a polyhedral Lyapunov function (PLF) implies …

We formulate a control problem for positive compartmental systems formed by nodes
(buffers) and arcs (flows). Our main result is that, on a finite horizon, we can solve the …

Signaling pathways represent parts of the global biological molecular network which
connects them into a seamless whole through complex direct and indirect (hidden) crosstalk …

Complex dynamical networks can often be analyzed as the interconnection of subsystems:
This allows us to considerably simplify the model and better understand the global behavior …

We consider the problem of assessing the sensitivity of uncertain biochemical systems in the
presence of input perturbations (either constant or periodic) around a stable steady state. In …

Given a static plant described by a differentiable input-output function, which is completely
unknown, but whose Jacobian takes values in a known polytope in the matrix space, this …

We present a systematic mathematical analysis of the qualitative steady‐state response to
rate perturbations in large classes of reaction networks. This includes multimolecular …