One of the most recent trends in cardiac electrophysiology is the development of integrative
anatomically accurate models of the heart, which include description of cardiac activity from …

In cardiac electrophysiology, there exist many sources of inter-and intra-personal variability.
These include variability in conditions and environment, and genotypic and molecular …

Chaste ('Cancer, heart and soft-tissue environment') is a software library and a set of test
suites for computational simulations in the domain of biology. Current functionality has …

Investigating the mechanisms underlying the genesis and conduction of electrical excitation
in the atria at physiological and pathological states is of great importance. To provide …

Biomedical science and its allied disciplines are entering a new era in which computational
methods and technologies are poised to play a prevalent role in supporting collaborative …

There is a need for, and utility in, the acquisition of data sets of cardiac histoanatomy, with
the vision of reconstructing individual hearts on the basis of noninvasive imaging, such as …

Computational models have become a fundamental tool in cardiac research. Models are
evolving to cover multiple scales and physical mechanisms. They are moving towards …

Cardiac rhythms arise from electrical activity generated by precisely timed opening and
closing of ion channels in individual cardiac myocytes. These impulses spread throughout …

Computational modelling of biological processes and systems has witnessed a remarkable
development in recent years. The search-term (modelling OR modeling) yields over 58 000 …

We developed a comprehensive cell model that simulates the sequential cellular events
from membrane excitation to contraction in the human ventricle. By combining this …