In vitro oxygen glucose deprivation model of ischemic stroke: a proteomics-driven systems biological perspective
Oxygen glucose deprivation (OGD) of brain cells is the commonest in vitro model of ischemic
stroke that is used extensively for basic and preclinical stroke research. Protein mass …
stroke that is used extensively for basic and preclinical stroke research. Protein mass …
A systematic review and in silico analysis of studies investigating the ischaemic penumbra proteome in animal models of experimental stroke
JV Moxon, C Pretorius, AF Trollope… - Journal of Cerebral …, 2024 - journals.sagepub.com
Ischaemic stroke results in the formation of a cerebral infarction bordered by an ischaemic
penumbra. Characterising the proteins within the ischaemic penumbra may identify neuro …
penumbra. Characterising the proteins within the ischaemic penumbra may identify neuro …
Quantitative proteomics revealed extensive microenvironmental changes after stem cell transplantation in ischemic stroke
Y Chen, F Song, M Tu, S Wu, X He, H Liu, C Xu… - Frontiers of …, 2022 - Springer
The local microenvironment is essential to stem cell-based therapy for ischemic stroke, and
spatiotemporal changes of the microenvironment in the pathological process provide vital …
spatiotemporal changes of the microenvironment in the pathological process provide vital …
Age-associated resilience against ischemic injury in mice exposed to transient middle cerebral artery occlusion
Ischemic stroke is the leading cause of death and disability. Although stroke mainly affects
aged individuals, animal research is mostly one on young rodents. Here, we examined the …
aged individuals, animal research is mostly one on young rodents. Here, we examined the …
Proteomic investigations of acute ischemic stroke in animal models: a narrative review
F Sun, RF Gu, R Wei - Journal of Bio-X Research, 2023 - spj.science.org
Acute ischemic stroke (AIS), a neurological injury resulting from blood clots, is the second
most common cause of death worldwide. Novel therapeutics are urgently needed. Rapid …
most common cause of death worldwide. Novel therapeutics are urgently needed. Rapid …
Hypoxia induced sex-difference in zebrafish brain proteome profile reveals the crucial role of H3K9me3 in recovery from acute hypoxia
Understanding the molecular basis of sex differences in neural response to acute hypoxic
insult has profound implications for the effective prevention and treatment of ischemic stroke …
insult has profound implications for the effective prevention and treatment of ischemic stroke …