Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Breast cancer is a major disease with high morbidity and mortality in women worldwide.
Increased use of imaging biomarkers has been shown to add more information with clinical …

Simple Summary Despite tremendous efforts in finding new therapeutic strategies and
promoting screening programs to increase early diagnosis, breast cancer is still a major …

Background Docetaxel (DOC) is widely used as a chemotherapy drug for various tumors,
including gastric cancer (GC), but the clinical application of DOC has been limited due to the …

Introduction: Molecular imaging is a fast developing field and there is a growing need for
specific imaging tracers in the clinic. Camelid single-domain antibody-fragments (sdAbs) …

Research on quantitative control of targeting effect for the drug delivery system of ligand-
conjugated nanoparticles of biodegradable polymers is at the cutting edge in the design of …

Yeast surface display libraries of human IgG1 Fc regions were prepared in which loop
sequences at the C-terminal tip of the CH3 domain were randomized. A high percentage of …

Molecular and non‐invasive imaging are rapidly emerging fields in preclinical cancer drug
discovery. This is driven by the need to develop more efficacious and safer treatments, the …

Antibodies and their derivatives radiolabelled with positron-and gamma-emitting
radiometals enable sensitive and quantitative molecular Positron Emission Tomography …

Affibody molecules are small and robust non-immunoglobulin affinity ligands capable of
binding to a wide range of protein targets. They are selected from combinatorial libraries …