Diffusion in the extracellular space (ECS) of the brain is constrained by the volume fraction
and the tortuosity and a modified diffusion equation represents the transport behavior of …

Memory decline in aging results from multiple factors that influence both executive function
and the medial temporal lobe memory system. In advanced aging, frontal-striatal systems …

The most unexpected and intriguing result from functional brain imaging studies of cognitive
aging is evidence for age-related overactivation: greater activation in older adults than in …

Partial least squares (PLS) analysis has been used to characterize distributed signals
measured by neuroimaging methods like positron emission tomography (PET), functional …

Basic cognitive functions, such as the abilities to activate, represent, maintain, focus and
process information, decline with age. A paradigm shift towards cross-level conceptions is …

During the course of normal aging, biological changes occur in the brain that are associated
with changes in cognitive ability. This review presents data from neuroimaging studies of …

This review summarizes our present knowledge about elderly people′ s problems with
walking. We highlight the plastic changes in the brain that allow a partial compensation of …

''Bigger is better.''So goes the message of many theoretical perspectives on working
memory, views that emphasize working memory as a ''mental workspace''which houses the …

Frontal contributions to cognitive decline in aging were explored using functional MRI.
Frontal regions active in younger adults during self-initiated (intentional) memory encoding …

This paper examines the investment decisions of older individual investors. We find that
older and experienced investors are more likely to follow rules of thumb that reflect greater …