Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases

P Kiessling, C Kuppe - Genome Medicine, 2024 - Springer
Spatial multi-omic studies have emerged as a promising approach to comprehensively
analyze cells in tissues, enabling the joint analysis of multiple data modalities like …

Next-Generation Sequencing-Based Spatial Transcriptomics: A Perspective from Barcoding Chemistry

W Shi, J Zhang, S Huang, Q Fan, J Cao, J Zeng, L Wu… - JACS Au, 2024 - ACS Publications
Gene expression profiling of tissue cells with spatial context is in high demand to reveal cell
types, locations, and intercellular or molecular interactions for physiological and …

Fully enclosed microbeads structured TENG arrays for omnidirectional wind energy harvesting with a portable galloping oscillator

LNY Cao, E Su, Z Xu, ZL Wang - Materials Today, 2023 - Elsevier
To facilitate the transition of triboelectric nanogenerators (TENG) from early stages to large-
scale real-world applications, urgent mass production is imperative, necessitating …

hadge: a comprehensive pipeline for donor deconvolution in single-cell studies

F Curion, X Wu, L Heumos, MMG André, L Halle… - Genome Biology, 2024 - Springer
Single-cell multiplexing techniques (cell hashing and genetic multiplexing) combine multiple
samples, optimizing sample processing and reducing costs. Cell hashing conjugates …

[HTML][HTML] Systematic benchmarking of imaging spatial transcriptomics platforms in FFPE tissues

H Wang, R Huang, J Nelson, C Gao, M Tran, A Yeaton… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Emerging imaging spatial transcriptomics (iST) platforms and coupled analytical methods
can recover cell-to-cell interactions, groups of spatially covarying genes, and gene …

Single-nucleus RNA-seq: Open the era of great navigation for FFPE tissue

Y Guo, W Wang, K Ye, L He, Q Ge, Y Huang… - International Journal of …, 2023 - mdpi.com
Single-cell sequencing (scRNA-seq) has revolutionized our ability to explore heterogeneity
and genetic variations at the single-cell level, opening up new avenues for understanding …

A roadmap for delivering a human musculoskeletal cell atlas

M Baldwin, CD Buckley, F Guilak, P Hulley… - Nature Reviews …, 2023 - nature.com
Advances in single-cell technologies have transformed the ability to identify the individual
cell types present within tissues and organs. The musculoskeletal bionetwork, part of the …

High‐Throughput Host–Microbe Single‐Cell RNA Sequencing Reveals Ferroptosis‐Associated Heterogeneity during Acinetobacter baumannii Infection

H Meng, T Zhang, Z Wang, Y Zhu, Y Yu… - Angewandte Chemie …, 2024 - Wiley Online Library
Interactions between host and bacterial cells are integral to human physiology. The
complexity of host–microbe interactions extends to different cell types, spatial aspects, and …

Single-cell RNA-seq reveals the metabolic status of immune cells response to immunotherapy in triple-negative breast cancer

PW Liu, J Lin, R Hou, Z Cai, Y Gong, PA He… - Computers in Biology …, 2024 - Elsevier
Immune checkpoint blockade (ICB) therapy offers promise in the treatment of triple-negative
breast cancer (TNBC); however, its limited efficacy in certain TNBC patients poses a …

Mapping Cell Atlases at the Single‐Cell Level

F Ye, J Wang, J Li, Y Mei, G Guo - Advanced Science, 2024 - Wiley Online Library
Recent advancements in single‐cell technologies have led to rapid developments in the
construction of cell atlases. These atlases have the potential to provide detailed information …