Nanomedicine combats drug resistance in lung cancer

X Zheng, X Song, G Zhu, D Pan, H Li, J Hu… - Advanced …, 2024 - Wiley Online Library
Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …

Efficacy and safety of first line treatments for patients with advanced epidermal growth factor receptor mutated, non-small cell lung cancer: systematic review and …

YI Zhao, J Liu, X Cai, Z Pan, J Liu, W Yin, H Chen, Z Xie… - Bmj, 2019 - bmj.com
Objective To compare the efficacy and safety of first line treatments for patients with
advanced epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer …

[HTML][HTML] Osimertinib treatment based on plasma T790M monitoring in patients with EGFR-mutant non-small-cell lung cancer (NSCLC): EORTC Lung Cancer Group …

J Remon, B Besse, SP Aix, A Callejo, K Al-Rabi… - Annals of …, 2023 - Elsevier
Background The APPLE trial aimed to evaluate the feasibility of longitudinal plasma
epidermal growth factor receptor (EGFR) T790M monitoring for the best sequencing strategy …

[HTML][HTML] Targeting HER2 alterations in non-small cell lung cancer: Therapeutic breakthrough and challenges

Y Yu, Y Yang, H Li, Y Fan - Cancer Treatment Reviews, 2023 - Elsevier
In non-small cell lung cancer (NSCLC) with human epidermal growth factor receptor 2
(HER2) alterations, chemotherapy remains the standard treatment over a decade, due to the …

Nanomedicine-based adjuvant therapy: a promising solution for lung cancer

Y Xu, JC Hsu, L Xu, W Chen, W Cai, K Wang - Journal of …, 2023 - Springer
Lung cancer has been the leading cause of cancer-related deaths worldwide for decades.
Despite the increasing understanding of the underlying disease mechanisms, the prognosis …

Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes

S Mirhadi, S Tam, Q Li, N Moghal, NA Pham… - Nature …, 2022 - nature.com
Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide. Only
a fraction of NSCLC harbor actionable driver mutations and there is an urgent need for …

Lung cancer treatment advances in 2022

F Abu Rous, EK Singhi, A Sridhar, MS Faisal… - Cancer …, 2023 - Taylor & Francis
The therapeutic landscape of lung cancer treatment is changing rapidly, and new data was
presented at the recently concluded American Society of Clinical Oncology 2022 (ASCO22) …

Current treatments for non-small cell lung cancer

Q Guo, L Liu, Z Chen, Y Fan, Y Zhou, Z Yuan… - Frontiers in …, 2022 - frontiersin.org
Despite improved methods of diagnosis and the development of different treatments,
mortality from lung cancer remains surprisingly high. Non-small cell lung cancer (NSCLC) …

Cigarette smoking, by accelerating the cell cycle, promotes the progression of non-small cell lung cancer through an HIF-1α-METTL3-m6A/CDK2AP2 axis

Y Yang, C Cheng, B He, X Du, J Liu, H Xia… - Journal of hazardous …, 2023 - Elsevier
Cigarette smoking killed about 8 million people every year and promoted non-small cell lung
cancer (NSCLC). We investigated the molecular mechanism of smoking-promoted NSCLC …

New update to the guidelines on testing predictive biomarkers in non-small-cell lung cancer: a National Consensus of the Spanish Society of Pathology and the …

D Isla, MD Lozano, L Paz-Ares, C Salas… - Clinical and …, 2023 - Springer
Non-small cell lung cancer (NSCLC) presents the greatest number of identified therapeutic
targets, some of which have therapeutic utility. Currently, detecting EGFR, BRAF, KRAS and …