Bacterial drug tolerance under clinical conditions is governed by anaerobic adaptation but not anaerobic respiration

CM Hemsley, JX Luo, CA Andreae… - Antimicrobial Agents …, 2014 - Am Soc Microbiol
Noninherited antibiotic resistance is a phenomenon whereby a subpopulation of genetically
identical bacteria displays phenotypic tolerance to antibiotics. We show here that compared …

Metabolomics Analysis of Bacterial Pathogen Burkholderia thailandensis and Mammalian Host Cells in Co-culture

N Aiosa, A Sinha, OA Jaiyesimi… - ACS Infectious …, 2022 - ACS Publications
The Tier 1 HHS/USDA Select Agent Burkholderia pseudomallei is a bacterial pathogen that
is highly virulent when introduced into the respiratory tract and intrinsically resistant to many …

Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulon

Y Chen, I Schröder, CT French, A Jaroszewicz… - BMC microbiology, 2014 - Springer
Background Burkholderia pseudomallei is a facultative intracellular pathogen and the
causative agent of melioidosis. A conserved type III secretion system (T3SS3) and type VI …

Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei

C Chewapreecha, AE Mather, SR Harris… - Communications …, 2019 - nature.com
The environmental bacterium Burkholderia pseudomallei causes melioidosis, an important
endemic human disease in tropical and sub-tropical countries. This bacterium occupies …

Deciphering the human antibody response against Burkholderia pseudomallei during melioidosis using a comprehensive immunoproteome approach

GE Wagner, TFP Stanjek, D Albrecht, M Lipp… - Frontiers in …, 2023 - frontiersin.org
Introduction The environmental bacterium Burkholderia pseudomallei causes the often fatal
and massively underreported infectious disease melioidosis. Antigens inducing protective …

Systematic Mutagenesis of Genes Encoding Predicted Autotransported Proteins of Burkholderia pseudomallei Identifies Factors Mediating Virulence in Mice, Net …

NRL Adler, MP Stevens, RE Dean, RJ Saint… - PLoS …, 2015 - journals.plos.org
Burkholderia pseudomallei is the causative agent of the severe tropical disease melioidosis,
which commonly presents as sepsis. The B. pseudomallei K96243 genome encodes eleven …

Transcriptional landscape of Burkholderia pseudomallei cultured under environmental and clinical conditions

C Kong, RR Wong, AK Ghazali, Y Hara… - Microbial …, 2023 - microbiologyresearch.org
Burkholderia pseudomallei, a Gram-negative pathogen, is the causative agent of
melioidosis in humans. This bacterium can be isolated from the soil, stagnant and salt-water …

Transcriptional profiling of Rickettsia prowazekii coding and non-coding transcripts during in vitro host-pathogen and vector-pathogen interactions

CLC Schroeder, HP Narra, A Sahni, K Khanipov… - Ticks and tick-borne …, 2017 - Elsevier
Natural pathogen transmission of Rickettsia prowazekii, the etiologic agent of epidemic
typhus, to humans is associated with arthropods, including human body lice, ticks, and …

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants [S]

CW Vander Broek, KJ Chalmers, MP Stevens… - Molecular & Cellular …, 2015 - ASBMB
Burkholderia pseudomallei is an intracellular pathogen and the causative agent of
melioidosis, a severe disease of humans and animals. One of the virulence factors critical for …

Burkholderia pseudomallei pathogenesis and survival in different niches

CH Yip, AK Ghazali, S Nathan - Biochemical Society …, 2020 - portlandpress.com
Burkholderia pseudomallei (Bp) is the causative agent of melioidosis, a disease of the
tropics with high clinical mortality rates. To date, no vaccines are approved for melioidosis …