Metal-based compounds in antiviral therapy

C Abate, F Carnamucio, O Giuffrè, C Foti - Biomolecules, 2022 - mdpi.com
In recent years, the study of metal complexes and metal-based nanomaterials has aroused
particular interest, leading to the promotion of new effective systems for the abatement of …

Complexes of ruthenium (II) as promising dual-active agents against cancer and viral infections

A D'Amato, A Mariconda, D Iacopetta, J Ceramella… - Pharmaceuticals, 2023 - mdpi.com
Poor responses to medical care and the failure of pharmacological treatment for many high-
frequency diseases, such as cancer and viral infections, have been widely documented. In …

Development of metal complexes for treatment of coronaviruses

HMA El-Lateef, T El-Dabea, MM Khalaf… - International Journal of …, 2022 - mdpi.com
Coronavirus disease (SARS-CoV-2) is a global epidemic. This pandemic, which has been
linked to high rates of death, has forced some countries throughout the world to implement …

A novel manganese (II) bisthiocarbohydrazone complex: Crystal structures, Hirshfeld surface analysis, DFT and molecular docking study with SARS-CoV-2

KKM Hashim, E Manoj, MRP Kurup - Journal of Molecular Structure, 2021 - Elsevier
A novel Mn (II) complex [Mn (H 2 L) Cl 2]• H 2 O (1) of a ditopic ligand 1, 5-bis (2-
benzoylpyridine) thiocarbohydrazone (H 2 L) was synthesized and characterised physico …

Synthesis, crystal structure, computational study and anti-virus effect of mixed ligand copper (II) complex with ONS donor Schiff base and 1, 10-phenanthroline

B Mohan, M Choudhary - Journal of Molecular Structure, 2021 - Elsevier
This work deals with the synthesis, crystal structure, computational study and antiviral
potential of mixed ligand copper (II) complex [Cu (L)(phen)](1),(where, H 2 L=(Z)-N'-((E)-2 …

Synthesis and characterization of novel copper (II) complexes as potential drug candidates against SARS-CoV-2 main protease

S Kumar, M Choudhary - New Journal of Chemistry, 2022 - pubs.rsc.org
Two novel copper (II) Schiff base complexes,[Cu (L1) 2](1) and [Cu (L2)(CH3OH)(Cl)](2) of
[(Z)-(5-chloro-2-((3, 5-dichloro-2-hydroxybenzylidene) amino) phenyl)(phenyl) methanone …

Towards understanding solvation effects on the conformational entropy of non-rigid molecules

J Gorges, S Grimme, A Hansen, P Pracht - … Chemistry Chemical Physics, 2022 - pubs.rsc.org
The absolute molecular entropy is a fundamental quantity for the accurate description of
thermodynamic properties. For non-rigid molecules, a substantial part of the entropy can be …

Synthesis, spectroscopic characterization, and thermal studies of novel Schiff base complexes: theoretical simulation studies on coronavirus (COVID-19) using …

YM Ahmed, MM Omar, GG Mohamed - Journal of the Iranian Chemical …, 2022 - Springer
Novel Schiff base ligand was prepared by the condensation of 2, 2-(ethylenedioxy) bis
(ethylamine) and imidazole-2-carboxaldehyde in a 1: 2 ratio, and its complexes with Cr (III) …

[HTML][HTML] Synthesis and characterization of violurate-based Mn (II) and Cu (II) complexes nano-crystallites as DNA-binders and therapeutics agents against SARS-CoV …

SA Al-Harbi - Journal of Saudi Chemical Society, 2022 - Elsevier
Synthesis and structural characterization of nano crystallites of bis-violurate-based
manganese (II) and copper (II) chelates is the subject of the present study. Analytical data …

Spectral, band gap and DFT studies of novel cobalt (II) complexes of N (4)-cyclohexylthiosemicarbazones: Molecular docking with DNA and SARS-CoV-2 Mpro

TM Kavya, LV Menon, KKM Hashim, E Manoj - Journal of Molecular …, 2024 - Elsevier
The synthesis and characterization of four novel cobalt complexes CoL 1 2 (1),[Co (HL 2) L
2] Cl (2), CoL 2 2 (3) and [Co (HL 2) L 2] Br (4) of thiosemicarbazones HL 1 and HL 2,(where …