Reducing the global burden of cardiovascular disease, part 2: prevention and treatment of cardiovascular disease

DP Leong, PG Joseph, M McKee, SS Anand… - Circulation …, 2017 - Am Heart Assoc
In this second part of a 2-part series on the global burden of cardiovascular disease, we
review the proven, effective approaches to the prevention and treatment of cardiovascular …

Evaluation and Management of Patients With Stable Angina: Beyond the Ischemia Paradigm: JACC State-of-the-Art Review

R Ferraro, JM Latina, A Alfaddagh, ED Michos… - Journal of the American …, 2020 - jacc.org
Coronary heart disease is a chronic, systemic disease with a wide range of associated
symptoms, clinical outcomes, and health care expenditure. Adverse events from coronary …

Days alive and out of hospital: exploring a patient-centered, pragmatic outcome in a clinical trial of patients with acute coronary syndromes

AC Fanaroff, D Cyr, ML Neely, J Bakal… - … Quality and Outcomes, 2018 - Am Heart Assoc
Background Cardiovascular clinical trials have traditionally incorporated separate time-to-
first-event analyses for their primary efficacy and safety comparisons, but this framework has …

Angina in 2022: Current perspectives

R Manfredi, M Verdoia, P Compagnucci… - Journal of clinical …, 2022 - mdpi.com
Angina is the main symptom of ischemic heart disease; mirroring a mismatch between
oxygen supply and demand. Epicardial coronary stenoses are only responsible for nearly …

血小板受体作为抗血小板治疗靶点的研究进展

舒雪梅, 郭涛 - 临床血液学杂志, 2020 - whuhzzs.com
血小板在血栓形成过程中发挥着重要的作用. 作用于血小板黏附, 聚集等过程的抗血小板药物能
有效地抑制体内血栓形成, 预防和治疗急性冠脉综合征和缺血性脑卒中, 抑制动脉粥样斑块破裂 …

Antithrombotic Treatment in Coronary Artery Disease

G Siasos, V Tsigkou, E Bletsa… - Current …, 2023 - ingentaconnect.com
Coronary artery disease exhibits growing mortality and morbidity worldwide despite the
advances in pharmacotherapy and coronary intervention. Coronary artery disease is …

Direct oral anticoagulants and coronary artery disease

R Choxi, K Kapoor, N Mackman… - … , thrombosis, and vascular …, 2022 - Am Heart Assoc
Coronary artery disease is a leading cause of morbidity and mortality worldwide. Acute
coronary syndrome as a first presentation is common and patients with established disease …

Fewer gastrointestinal bleeds with ticagrelor and prasugrel compared with clopidogrel in patients with acute coronary syndrome following percutaneous coronary …

NS Abraham, EH Yang, PA Noseworthy… - Alimentary …, 2020 - Wiley Online Library
Background Gastrointestinal bleeding (GIB) frequently occurs following percutaneous
coronary intervention (PCI) for acute coronary syndrome (ACS) with the prescription of …

Optimal Medical Therapy for Chronic Coronary Disease in 2024: Focus on Antithrombotic Therapy

PP Patel, AC Fanaroff - Medical Clinics, 2024 - medical.theclinics.com
Patients with previous myocardial infarction (MI) are at high risk of recurrent MI, stroke, and
cardiovascular death, with a 5-year risk of nearly 40%. Although the highest risk period is …

Anti‐platelet agents: past, present and future

D Cox - ISBT Science Series, 2020 - Wiley Online Library
The discovery of the role of platelets in cardiovascular disease led to the introduction of
aspirin as a therapeutic agent for heart disease. Aspirin has proven to be effective in …