Testing at scale during the COVID-19 pandemic

TR Mercer, M Salit - Nature Reviews Genetics, 2021 - nature.com
Assembly and publication of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome in January 2020 enabled the immediate development of tests to detect the …

Phylogenetic and phylodynamic approaches to understanding and combating the early SARS-CoV-2 pandemic

SW Attwood, SC Hill, DM Aanensen… - Nature Reviews …, 2022 - nature.com
Determining the transmissibility, prevalence and patterns of movement of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …

[HTML][HTML] Outbreak caused by the SARS-CoV-2 Omicron variant in Norway, November to December 2021

LT Brandal, E MacDonald, L Veneti, T Ravlo… - …, 2021 - eurosurveillance.org
In late November 2021, an outbreak of Omicron SARS-CoV-2 following a Christmas party
with 117 attendees was detected in Oslo, Norway. We observed an attack rate of 74% and …

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

TM Delorey, CGK Ziegler, G Heimberg, R Normand… - Nature, 2021 - nature.com
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress
syndrome and multiple organ failure,,–, but little is known about its pathophysiology. Here …

[HTML][HTML] Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

WF Garcia-Beltran, EC Lam, KS Denis, AD Nitido… - Cell, 2021 - cell.com
Vaccination elicits immune responses capable of potently neutralizing SARS-CoV-2.
However, ongoing surveillance has revealed the emergence of variants harboring mutations …

Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

NL Welch, M Zhu, C Hua, J Weller, ME Mirhashemi… - Nature medicine, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has demonstrated a clear
need for high-throughput, multiplexed and sensitive assays for detecting severe acute …

Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants

J Arizti-Sanz, AD Bradley, YB Zhang… - Nature biomedical …, 2022 - nature.com
The widespread transmission and evolution of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) call for rapid nucleic acid diagnostics that are easy to use …

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

CGK Ziegler, VN Miao, AH Owings, AW Navia, Y Tang… - Cell, 2021 - cell.com
SARS-CoV-2 infection can cause severe respiratory COVID-19. However, many individuals
present with isolated upper respiratory symptoms, suggesting potential to constrain viral …

SARS-CoV-2 vaccines and the growing threat of viral variants

JP Moore, PA Offit - Jama, 2021 - jamanetwork.com
In November 2019, a bat coronavirus made its debut in the human population. Since that
time, the virus has continued to adapt, resulting in a series of viral variants. The question that …

COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask …

K Escandón, AL Rasmussen, II Bogoch… - BMC infectious …, 2021 - Springer
Scientists across disciplines, policymakers, and journalists have voiced frustration at the
unprecedented polarization and misinformation around coronavirus disease 2019 (COVID …