Dopamine receptors are belong to the family of G protein-coupled receptor. There are five
types of dopamine receptor (DR), including DRD1, DRD2, DRD3, DRD4, and DRD5, which …

Colorectal cancer (CRC) is among the five most commonly diagnosed cancers worldwide,
constituting 6% of all cancers and the third leading cause of cancer death. CRC is the third …

TGF-β is a promising immunotherapeutic target. It is expressed ubiquitously in a latent form
that must be activated to function. Determination of where and how latent TGF-β (L-TGF-β) is …

Hepatocellular carcinoma (HCC) is a common type of malignant tumor with an extremely
poor prognosis. Because many HCC patients are diagnosed with advanced disease …

Hepatocellular carcinoma (HCC) is frequently characterized by metabolic and immune
remodeling in the tumor microenvironment. We previously discovered that liver-specific …

Natural killer (NK) cell-based immunotherapy is a promising approach for treating solid
tumors and hematological malignancies. However, its therapeutic efficacy is limited by poor …

Varicella zoster virus behaves differently from other herpes viruses as it differs from them in
many aspects. Recently, there has been growing evidence on the beneficial effects of the …

The action of the immune system against neoplastic diseases has become one of the main
sources of research. The biological pathways of this system are known to contribute in …

Cancer is a multifaceted disease influenced by both intrinsic cellular traits and extrinsic
factors, with the tumor microenvironment (TME) being crucial in its progression. To satisfy …

Objective To evaluate the expression of C‐C motif chemokine ligand 5 (CCL5) in
hepatocellular carcinoma (HCC) and to explore its role in regulating the immune …