Sickle cell anaemia (SCA) stands as a hereditary blood disorder characterized by mutated
haemoglobin, causing red blood cells to adopt a sickle shape, leading to complications like …

Tranexamic acid (TXA) is a potent antifibrinolytic with documented efficacy in reducing blood
loss and allogeneic red blood cell transfusion in several clinical settings. With a growing …

Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Importance Red blood cell transfusion is a common medical intervention with benefits and
harms. Objective To provide recommendations for use of red blood cell transfusion in adults …

Importance Red blood cell (RBC) transfusion is common among patients admitted to the
intensive care unit (ICU). Despite multiple randomized clinical trials of hemoglobin (Hb) …

Abstract Purpose of Review Multiple guidelines and recommendations have been written to
address the perioperative management of antiplatelet and anticoagulant drugs. In this …

Vasoplegic syndrome (VS) is a common complication following cardiovascular surgery with
cardiopulmonary bypass (CPB), and its incidence varies from 5 to 44%. It is defined as a …

Inherited and acquired coagulopathy are frequently associated with major bleeding in
severe trauma, cardiac surgery with cardiopulmonary bypass, and postpartum hemorrhage …

Viscoelastic coagulation tests have been increasingly used for hemostasis management in
cardiac surgery. The ClotPro system is a novel viscoelastic device based on principles of …

The use of heparin for anticoagulation has changed the face of cardiac surgery by allowing
a bloodless and motionless surgical field throughout the introduction of cardiopulmonary …