The relevance of bioinformatics applications in the discovery of vaccine candidates and potential drugs for COVID-19 treatment
OS Chukwudozie, VC Duru… - … and Biology Insights, 2021 - journals.sagepub.com
The application of bioinformatics to vaccine research and drug discovery has never been so
essential in the fight against infectious diseases. The greatest combat of the 21st century …
essential in the fight against infectious diseases. The greatest combat of the 21st century …
[HTML][HTML] In silico analysis of epitope-based vaccine candidate against tuberculosis using reverse vaccinology
Tuberculosis (TB) kills more individuals in the world than any other disease, and a threat
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …
made direr by the coverage of drug-resistant strains of Mycobacterium tuberculosis (Mtb) …
The COVID-19 vaccine development: a pandemic paradigm
DC Carneiro, JD Sousa, JP Monteiro-Cunha - Virus Research, 2021 - Elsevier
COVID-19 pandemic has resulted in millions of deaths and a social-economic crisis. A
worldwide effort was made to develop efficient vaccines for this disease. A vaccine should …
worldwide effort was made to develop efficient vaccines for this disease. A vaccine should …
[HTML][HTML] Immunoinformatics design of a novel epitope-based vaccine candidate against dengue virus
AO Fadaka, NRS Sibuyi, DR Martin, M Goboza… - Scientific reports, 2021 - nature.com
Dengue poses a global health threat, which will persist without therapeutic intervention.
Immunity induced by exposure to one serotype does not confer long-term protection against …
Immunity induced by exposure to one serotype does not confer long-term protection against …
Immunoinformatics-guided designing of epitope-based subunit vaccines against the SARS Coronavirus-2 (SARS-CoV-2)
Abstract SARS Coronavirus-2 (SARS-CoV-2) pandemic has become a global issue which
has raised the concern of scientific community to design and discover a counter-measure …
has raised the concern of scientific community to design and discover a counter-measure …
[HTML][HTML] Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach
M Alizadeh, H Amini-Khoei, S Tahmasebian… - Scientific reports, 2022 - nature.com
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …
outbreaks have been documented, the majority of which have occurred in Central Africa …
[HTML][HTML] In-silico designing of epitope-based vaccine against the seven banded grouper nervous necrosis virus affecting fish species
Neural necrosis virus (NNV) of family Nodaviridae affect wide range of fish species with viral
encephalopathy and retinopathy causing mass mortality up to 100%. Currently there is no …
encephalopathy and retinopathy causing mass mortality up to 100%. Currently there is no …
In-silico design of a multivalent epitope-based vaccine against Candida auris
Candida auris is a rapidly emerging human pathogenic fungus with a high mortality rate.
Recent report suggests that the new clinical isolates are showing resistance to the major …
Recent report suggests that the new clinical isolates are showing resistance to the major …
[HTML][HTML] Designing multi-epitope-based vaccine targeting surface immunogenic protein of Streptococcus agalactiae using immunoinformatics to control mastitis in …
Background Milk provides energy as well as the basic nutrients required by the body. In
particular, milk is beneficial for bone growth and development in children. Based on …
particular, milk is beneficial for bone growth and development in children. Based on …
[HTML][HTML] Identification of Putative Vaccine and Drug Targets against the Methicillin-Resistant Staphylococcus aureus by Reverse Vaccinology and Subtractive …
Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen and
responsible for causing life-threatening infections. The emergence of hypervirulent and …
responsible for causing life-threatening infections. The emergence of hypervirulent and …