Recent developments on therapeutic and diagnostic approaches for COVID-19

J Majumder, T Minko - The AAPS journal, 2021 - Springer
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made a serious public health …

SARS‐CoV‐2‐neutralising monoclonal antibodies for treatment of COVID‐19

KL Chai, E Tomlinson, Z Khosravi… - Cochrane Database …, 2021 - cochranelibrary.com
Background Monoclonal antibodies (mAbs) are laboratory‐produced molecules derived
from the B cells of an infected host. They are being investigated as a potential therapy for …

[HTML][HTML] Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and …

MU Mirza, M Froeyen - Journal of pharmaceutical analysis, 2020 - Elsevier
Recently emerged SARS-CoV-2 caused a major outbreak of coronavirus disease 2019
(COVID-19) and instigated a widespread fear, threatening global health safety. To date, no …

An automatic approach based on CNN architecture to detect Covid-19 disease from chest X-ray images

S Hira, A Bai, S Hira - Applied Intelligence, 2021 - Springer
Abstract Novel coronavirus (COVID-19) is started from Wuhan (City in China), and is rapidly
spreading among people living in other countries. Today, around 215 countries are affected …

HPLC-UV method for quantification of favipiravir in pharmaceutical formulations

İ Bulduk - Acta Chromatographica, 2021 - akjournals.com
Favipiravir (FVP), a pyrazine analog, has shown antiviral activity against a wide variety of
viruses. It is considered to be worth further investigation as a potential candidate drug for …

Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection

P Padmanabhan, R Desikan… - PLoS computational …, 2020 - journals.plos.org
The entry of SARS-CoV-2 into target cells requires the activation of its surface spike protein,
S, by host proteases. The host serine protease TMPRSS2 and cysteine proteases Cathepsin …

Medical imaging with deep learning for COVID-19 diagnosis: a comprehensive review

S Bharati, P Podder, M Mondal, VB Prasath - arXiv preprint arXiv …, 2021 - arxiv.org
The outbreak of novel coronavirus disease (COVID-19) has claimed millions of lives and has
affected all aspects of human life. This paper focuses on the application of deep learning …

Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CLpro

MA Alamri, M Tahir ul Qamar, MU Mirza… - Journal of …, 2021 - Taylor & Francis
The SARS-CoV-2 was confirmed to cause the global pandemic of coronavirus disease 2019
(COVID-19). The 3-chymotrypsin-like protease (3CLpro), an essential enzyme for viral …

[HTML][HTML] COVID-19 en pediatría: aspectos clínicos, epidemiológicos, inmunopatogenia, diagnóstico y tratamiento

J Acosta Torres, M Pérez Cutiño… - Revista Cubana de …, 2020 - scielo.sld.cu
RESUMEN Introducción: La Organización Mundial de la Salud declaró desde el 11 de
marzo de 2020 la infección por el coronavirus denominado SARS-CoV-2, como una …

A time series method to analyze incidence pattern and estimate reproduction number of COVID-19

S Deb, M Majumdar - arXiv preprint arXiv:2003.10655, 2020 - arxiv.org
The ongoing pandemic of Coronavirus disease (COVID-19) emerged in Wuhan, China in
the end of 2019. It has already affected more than 300,000 people, with the number of …