An fMRI-based neurologic signature of physical pain
Background Persistent pain is measured by means of self-report, the sole reliance on which
hampers diagnosis and treatment. Functional magnetic resonance imaging (fMRI) holds …
hampers diagnosis and treatment. Functional magnetic resonance imaging (fMRI) holds …
The contextual brain: implications for fear conditioning, extinction and psychopathology
Contexts surround and imbue meaning to events; they are essential for recollecting the past,
interpreting the present and anticipating the future. Indeed, the brain's capacity to …
interpreting the present and anticipating the future. Indeed, the brain's capacity to …
Neuropathic pain: mechanisms and their clinical implications
Neuropathic pain can develop after nerve injury, when deleterious changes occur in injured
neurons and along nociceptive and descending modulatory pathways in the central nervous …
neurons and along nociceptive and descending modulatory pathways in the central nervous …
[HTML][HTML] Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data
The brain systems underlying placebo analgesia are insufficiently understood. Here we
performed a systematic, participant-level meta-analysis of experimental functional …
performed a systematic, participant-level meta-analysis of experimental functional …
Mindfulness meditation-based pain relief employs different neural mechanisms than placebo and sham mindfulness meditation-induced analgesia
Mindfulness meditation reduces pain in experimental and clinical settings. However, it
remains unknown whether mindfulness meditation engages pain-relieving mechanisms …
remains unknown whether mindfulness meditation engages pain-relieving mechanisms …
Anterior insular cortex and emotional awareness
This paper reviews the foundation for a role of the human anterior insular cortex (AIC) in
emotional awareness, defined as the conscious experience of emotions. We first introduce …
emotional awareness, defined as the conscious experience of emotions. We first introduce …
Alterations in resting-state functional connectivity link mindfulness meditation with reduced interleukin-6: A randomized controlled trial
Background Mindfulness meditation training interventions have been shown to improve
markers of health, but the underlying neurobiological mechanisms are not known. Building …
markers of health, but the underlying neurobiological mechanisms are not known. Building …
The search for pain biomarkers in the human brain
A Mouraux, GD Iannetti - Brain, 2018 - academic.oup.com
Non-invasive functional brain imaging is used more than ever to investigate pain in health
and disease, with the prospect of finding new means to alleviate pain and improve patient …
and disease, with the prospect of finding new means to alleviate pain and improve patient …
Mindfulness meditation–based pain relief: a mechanistic account
Pain is a multidimensional experience that involves interacting sensory, cognitive, and
affective factors, rendering the treatment of chronic pain challenging and financially …
affective factors, rendering the treatment of chronic pain challenging and financially …
The pervasive problem with placebos in psychology: Why active control groups are not sufficient to rule out placebo effects
To draw causal conclusions about the efficacy of a psychological intervention, researchers
must compare the treatment condition with a control group that accounts for improvements …
must compare the treatment condition with a control group that accounts for improvements …