Heterotopic ossification: a comprehensive review

C Meyers, J Lisiecki, S Miller, A Levin, L Fayad… - JBMR …, 2019 - Wiley Online Library
Heterotopic ossification (HO) is a diverse pathologic process, defined as the formation of
extraskeletal bone in muscle and soft tissues. HO can be conceptualized as a tissue repair …

Heterotopic ossification: basic-science principles and clinical correlates

K Ranganathan, S Loder, S Agarwal, VW Wong… - JBJS, 2015 - journals.lww.com
Heterotopic ossification is the formation of ectopic lamellar bone in soft tissues. It is
increasingly recognized as a complication following trauma, burns, neurologic injuries, and …

Heterotopic ossification revisited

AF Mavrogenis, PN Soucacos… - …, 2011 - journals.healio.com
Heterotopic ossification is the abnormal formation of mature lamellar bone within
extraskeletal soft tissues where bone does not exist. Heterotopic ossification has been …

Pathophysiology and emerging molecular therapeutic targets in heterotopic ossification

F Felix-Ilemhenbhio, GAE Pickering… - International Journal of …, 2022 - mdpi.com
The term heterotopic ossification (HO) describes bone formation in tissues where bone is
normally not present. Musculoskeletal trauma induces signalling events that in turn trigger …

Heterotopic ossification and the elucidation of pathologic differentiation

D Cholok, MT Chung, K Ranganathan, S Ucer, D Day… - Bone, 2018 - Elsevier
Tissue regeneration following acute or persistent inflammation can manifest a spectrum of
phenotypes ranging from the adaptive to the pathologic. Heterotopic Ossification (HO), the …

Post‐traumatic heterotopic ossification: an old problem in need of new solutions

N Eisenstein, S Stapley, L Grover - Journal of Orthopaedic …, 2018 - Wiley Online Library
Heterotopic ossification (HO) is the formation of pathological bone in ectopic sites and it can
have serious consequences for functional outcomes. For many years, its main clinical …

Risk factors for the development of heterotopic ossification in seriously burned adults: A National Institute on Disability, Independent Living and Rehabilitation …

B Levi, P Jayakumar, A Giladi, JB Jupiter… - Journal of Trauma …, 2015 - journals.lww.com
BACKGROUND Heterotopic ossification (HO) is a debilitating complication of burn injury;
however, incidence and risk factors are poorly understood. In this study, we use a …

The development and impact of heterotopic ossification in burns: a review of four decades of research

R Kornhaber, N Foster, D Edgar… - Scars, burns & …, 2017 - journals.sagepub.com
Introduction: Heterotopic ossification (HO) is the formation of lamellar bone within connective
and other tissue where bone should not form and is a rare complication after burn injury …

Predicting heterotopic ossification early after burn injuries: a risk scoring system

JC Schneider, LC Simko, R Goldstein, VL Shie… - Annals of …, 2017 - journals.lww.com
Objective: The purpose of this study is to develop a scoring system that stratifies burn
patients at the time of hospital admission according to risk of developing heterotopic …

Long-term outcomes in burn patients

J Bryarly, K Kowalske - Surgical Clinics, 2023 - surgical.theclinics.com
Since the 1970s, there has been an increased awareness of the importance of nonsurgical
interventions for burn care. Physical and occupational therapies have become mainstays in …