Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

Alzheimer's disease (AD) is an age‐associated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …

Cholesterol homeostasis is vital for brain function. Brain cholesterol is locally synthesized,
with varying synthesis capacities across different cell types. Moreover, brain cholesterol …

Alzheimer's disease is a progressive brain disease that is becoming a major health problem
in today's world due to the aging population. Despite it being widely known that diet has a …

Alzheimer's disease (AD) is the most common form of dementia in the elderly population,
affecting over 55 million people worldwide. Histopathological hallmarks of this multifactorial …

Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disorder.
Most existing treatments only provide symptomatic solutions. Here, we introduce currently …

Alzheimer's disease (AD) is characterized by amyloid plaques and neurofibrillary tangles, in
addition to neuroinflammation and changes in brain lipid metabolism. 25 …

Disturbances of lipid homeostasis in cells provoke human diseases. The elucidation of the
underlying mechanisms and the development of efficient therapies represent formidable …

Alzheimer's disease (AD) is the most common neurodegenerative disorder, which is
associated with memory deficit and global cognitive decline. Age is the greatest risk factor …

Amyloid PET imaging has been crucial for detecting the accumulation of amyloid beta (Aβ)
deposits in the brain and to study Alzheimer's disease (AD). We performed a genome-wide …