The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …
The vaginal microbiota, host defence and reproductive physiology
The interaction between the human host and the vaginal microbiota is highly dynamic. Major
changes in the vaginal physiology and microbiota over a woman's lifetime are largely …
changes in the vaginal physiology and microbiota over a woman's lifetime are largely …
Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics
Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
Prevalence and clinical significance of sterile intra‐amniotic inflammation in patients with preterm labor and intact membranes
Problem Inflammation and infection play a major role in preterm birth. The purpose of this
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …
Intrauterine infection and preterm delivery
RL Goldenberg, JC Hauth… - New England journal of …, 2000 - Mass Medical Soc
Preterm delivery is the chief problem in obstetrics today, accounting for 70 percent of
perinatal mortality and nearly half of long-term neurologic morbidity. 1, 2 Approximately 10 …
perinatal mortality and nearly half of long-term neurologic morbidity. 1, 2 Approximately 10 …
[PDF][PDF] Preterm birth: causes, consequences, and prevention
RE Behrman, AS Butler - 2007 - cds.psych.ucla.edu
Although individual behaviors have not been proven to have a strong influence on the risk of
preterm birth, consistent evidence suggests that a constellation of favorable lifestyle factors …
preterm birth, consistent evidence suggests that a constellation of favorable lifestyle factors …
The preterm parturition syndrome
The implicit paradigm that has governed the study and clinical management of preterm
labour is that term and preterm parturition are the same processes, except for the gestational …
labour is that term and preterm parturition are the same processes, except for the gestational …
Amniotic fluid infection, inflammation, and colonization in preterm labor with intact membranes
Objective The purpose of this study was to compare intraamniotic inflammation vs microbial
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …
The role of inflammation and infection in preterm birth
Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labor and …
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labor and …