With the in-depth understanding of the anti-cancer immunity, immunotherapy has become a
promising cancer treatment after surgery, radiotherapy, and chemotherapy. As natural …

The tumor microenvironment (TME) plays an important role in various stages of tumor
generation, metastasis, and evasion of immune monitoring and treatment. TME targeted …

Many systemically administered cancer therapies exhibit dose-limiting toxicities that reduce
their effectiveness. To increase efficacy, bacterial delivery platforms have been developed …

Natural bacteria have been utilized to directly maintain the human body's homeostasis for
directly or indirectly relieving diseases throughout history. With the rapid development of …

Efficacy of immune checkpoint inhibitors in cancers can be limited by CD8 T cell dysfunction
or HLA-I down-regulation. Tumor control mechanisms independent of CD8/HLA-I axis would …

Colorectal cancer (CRC) is a common malignancy of the gastrointestinal tract, accounting for
the second most common cause of gastrointestinal tumors. As one of the intestinal barriers …

Photothermal therapy (PTT) is a new treatment modality for tumors. However, the efficient
delivery of photothermal agents into tumors remains difficult, especially in hypoxic tumor …

Simple Summary Pancreatic cancer is a devasting disease that has unfortunately proven
very difficult to treat. Exploring new therapeutic options and getting an early diagnosis is …

Typical physiological characteristics of tumors, such as weak acidity, low oxygen content,
and upregulation of certain enzymes in the tumor microenvironment (TME), provide survival …

As the limitations of cancer immunotherapy become increasingly apparent, there is
considerable anticipation regarding the utilization of biological tools to enhance treatment …