Therapeutic potential of quercetin as a cardiovascular agent

RV Patel, BM Mistry, SK Shinde, R Syed… - European journal of …, 2018 - Elsevier
Flavonoids are integral components of various vegetation and in foods; consequently, they
represent an inevitable part of the diet. Historical and epidemiological proof recommend that …

A review of traditional uses, phytochemistry and pharmacology of the genus Indigofera

E Gerometta, I Grondin, J Smadja, M Frederich… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Indigofera is the third-largest genus in the family of
Fabaceae, with approximately 750 species. It is distributed across all tropical regions …

Promising phytochemicals of traditional Indian herbal steam inhalation therapy to combat COVID-19–An in silico study

S Gowrishankar, S Muthumanickam… - Food and Chemical …, 2021 - Elsevier
Background COVID-19, the presently prevailing global public health emergency has
culminated in international instability in economy. This unprecedented pandemic outbreak …

Machine learning-based virtual screening for STAT3 anticancer drug target

A Wadood, A Ajmal, M Junaid… - Current …, 2022 - ingentaconnect.com
Background: Signal transducers and activators of the transcription (STAT) family is
composed of seven structurally similar and highly conserved members, including STAT1 …

Synthesis of new derivatives of benzylidinemalononitrile and ethyl 2-cyano-3-phenylacrylate: in silico anticancer evaluation

KM Uddin, M Sakib, S Siraji, R Uddin, S Rahman… - ACS …, 2023 - ACS Publications
In this study, microwave-assisted Knoevenagel condensation was used to produce two
novel series of derivatives (1–6) from benzylidenemalononitrile and ethyl 2-cyano-3 …

Computational multi‐target approach to target essential enzymes of Leishmania donovani using comparative molecular dynamic simulations and MMPBSA analysis

D Saha, A Nath Jha - Phytochemical Analysis, 2023 - Wiley Online Library
Introduction Visceral leishmaniasis (VL) is caused by Leishmania donovani. The purine and
pyrimidine pathways are essential for L. donovani. Simultaneously inhibiting multiple targets …

Senyawa pada serbuk rimpang kunyit (Curcuma longa L.) yang berpotensi sebagai antioksidan

T Suprihatin, S Rahayu, M Rifa'i… - Buletin Anatomi dan …, 2020 - ejournal2.undip.ac.id
Tanaman kunyit secara tradisional sudah sejak lama banyak digunakan sebagai tanaman
obat. Negara India dan China menggunakan tanaman kunyit untuk mengobati penyakit …

Novel N-sulfonylphthalimides: Efficient synthesis, X-ray characterization, spectral investigations, POM analyses, DFT computations and antibacterial activity

I Grib, M Berredjem, KO Rachedi, SE Djouad… - Journal of Molecular …, 2020 - Elsevier
Some novel N-sulfonylphthalimides were synthesized in good yields by condensation of
anhydride phthalic with various sulfonamides by two different methods: conventional …

Novel phthalimide based analogues: Design, synthesis, biological evaluation, and molecular docking studies

IMM Othman, MAM Gad-Elkareem… - Journal of enzyme …, 2019 - Taylor & Francis
Pyrazolylphthalimide derivative 4 was synthesized and reacted with different reagents to
afford the target compounds imidazopyrazoles 5-7, pyrazolopyrimidines 9, 12, 14 and …

Structural and biofunctional insights into the Cyclo (Pro-Pro-Phe-Phe-) Scaffold from experimental and in silico studies: Melanoma and beyond

J Bojarska, M Breza, M Remko, M Czyz… - International Journal of …, 2022 - mdpi.com
Short peptides have great potential as safe and effective anticancer drug leads. Herein, the
influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient …