The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …

Acute pulmonary embolism: a review

Y Freund, F Cohen-Aubart, B Bloom - Jama, 2022 - jamanetwork.com
Importance Pulmonary embolism (PE) is characterized by occlusion of blood flow in a
pulmonary artery, typically due to a thrombus that travels from a vein in a lower limb. The …

Antithrombotic therapy for VTE disease: second update of the CHEST guideline and expert panel report

SM Stevens, SC Woller, LB Kreuziger, H Bounameaux… - Chest, 2021 - Elsevier
Background This is the 2nd update to the 9th edition of these guidelines. We provide
recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions …

Executive summary: antithrombotic therapy for VTE disease: second update of the CHEST guideline and expert panel report

SM Stevens, SC Woller, LB Kreuziger, H Bounameaux… - Chest, 2021 - Elsevier
Background This is the 2nd update to the 9th edition of these guidelines. We provide
recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions …

American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism

TL Ortel, I Neumann, W Ageno, R Beyth… - Blood …, 2020 - ashpublications.org
In August 2022, these guidelines were reviewed by an expert work group convened by ASH.
Review included limited searches for new evidence and discussion of the search results …

2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) The …

SV Konstantinides, G Meyer, C Becattini… - European heart …, 2020 - academic.oup.com
determination and the implementation of preventive, diagnostic or therapeutic medical
strategies. However, the ESC Guidelines do not override in any way whatsoever the …

Indigo aspiration system for treatment of pulmonary embolism: results of the EXTRACT-PE trial

AK Sista, JM Horowitz, VF Tapson, M Rosenberg… - Cardiovascular …, 2021 - jacc.org
Objectives This study sought to prospectively evaluate the safety and efficacy of the Indigo
aspiration system in submassive acute pulmonary embolism (PE). Background PE treatment …

Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism: the FOCUS study

L Valerio, AC Mavromanoli, S Barco… - European heart …, 2022 - academic.oup.com
Aims To systematically assess late outcomes of acute pulmonary embolism (PE) and to
investigate the clinical implications of post-PE impairment (PPEI) fulfilling prospectively …

[HTML][HTML] Ultrasound-facilitated, catheter-directed thrombolysis vs anticoagulation alone for acute intermediate-high-risk pulmonary embolism: Rationale and design of …

FA Klok, G Piazza, ASP Sharp, FN Ainle, MR Jaff… - American Heart …, 2022 - Elsevier
Background Due to the bleeding risk of full-dose systemic thrombolysis and the lack of major
trials focusing on the clinical benefits of catheter-directed treatment, heparin …

Trends in thrombolytic treatment and outcomes of acute pulmonary embolism in Germany

K Keller, L Hobohm, M Ebner, KP Kresoja… - European heart …, 2020 - academic.oup.com
Aims Pulmonary embolism (PE) is the third most common cardiovascular cause of death;
systemic thrombolysis is potentially lifesaving treatment in patients presenting with …