Gene drives gaining speed
E Bier - Nature Reviews Genetics, 2022 - nature.com
Gene drives are selfish genetic elements that are transmitted to progeny at super-Mendelian
(> 50%) frequencies. Recently developed CRISPR–Cas9-based gene-drive systems are …
(> 50%) frequencies. Recently developed CRISPR–Cas9-based gene-drive systems are …
Resistance to natural and synthetic gene drive systems
Scientists are rapidly developing synthetic gene drive elements intended for release into
natural populations. These are intended to control or eradicate disease vectors and pests, or …
natural populations. These are intended to control or eradicate disease vectors and pests, or …
Expansion and loss of sperm nuclear basic protein genes in Drosophila correspond with genetic conflicts between sex chromosomes
Many animal species employ sperm nuclear basic proteins (SNBPs) or protamines to
package sperm genomes tightly. SNBPs vary across animal lineages and evolve rapidly in …
package sperm genomes tightly. SNBPs vary across animal lineages and evolve rapidly in …
Impacts of sex ratio meiotic drive on genome structure and function in a stalk-eyed fly
Stalk-eyed flies in the genus Teleopsis carry selfish genetic elements that induce sex ratio
(SR) meiotic drive and impact the fitness of male and female carriers. Here, we assemble …
(SR) meiotic drive and impact the fitness of male and female carriers. Here, we assemble …
[HTML][HTML] Paternal genome elimination: patterns and mechanisms of drive and silencing
M Herbette, L Ross - Current Opinion in Genetics & Development, 2023 - Elsevier
In thousands of arthropod species, males inherit, but subsequently eliminate the entire
haploid genome of their father. However, why this peculiar reproductive strategy evolved …
haploid genome of their father. However, why this peculiar reproductive strategy evolved …
Gene drive: progress and prospects
Gene drive is a naturally occurring phenomenon in which selfish genetic elements
manipulate gametogenesis and reproduction to increase their own transmission to the next …
manipulate gametogenesis and reproduction to increase their own transmission to the next …
Unique structure and positive selection promote the rapid divergence of Drosophila Y chromosomes
Y chromosomes across diverse species convergently evolve a gene-poor, heterochromatic
organization enriched for duplicated genes, LTR retrotransposons, and satellite DNA …
organization enriched for duplicated genes, LTR retrotransposons, and satellite DNA …
The wtf meiotic driver gene family has unexpectedly persisted for over 100 million years
M De Carvalho, GS Jia, AN Srinivasa, RB Billmyre… - Elife, 2022 - elifesciences.org
Meiotic drivers are selfish elements that bias their own transmission into more than half of
the viable progeny produced by a driver+/driver− heterozygote. Meiotic drivers are thought …
the viable progeny produced by a driver+/driver− heterozygote. Meiotic drivers are thought …
Selfing is the safest sex for Caenorhabditis tropicalis
Mating systems have profound effects on genetic diversity and compatibility. The convergent
evolution of self-fertilization in three Caenorhabditis species provides a powerful lens to …
evolution of self-fertilization in three Caenorhabditis species provides a powerful lens to …
[HTML][HTML] New perspectives on the causes and consequences of male meiotic drive
Gametogenesis is vulnerable to selfish genetic elements that bias their transmission to the
next generation by cheating meiosis. These so-called meiotic drivers are widespread in …
next generation by cheating meiosis. These so-called meiotic drivers are widespread in …