Sinonasal malignancies make up< 5% of all head and neck neoplasms, with an incidence of
0.5–1.0 per 100,000. The outcome of these rare malignancies has been poor, whereas …

Purpose of review Mucosal melanoma is of great interest due to its aggressive behavior and
less favorable prognosis. The literature is mainly case reports and case series. Here, we will …

Mucosal melanoma of the head and neck is a very rare and aggressive malignancy with a
very poor prognosis. The nasal cavity, paranasal sinuses, and oral cavity are the most …

Mucosal melanoma (MM) is a rare melanoma subtype that originates from melanocytes
within sun-protected mucous membranes. Compared with cutaneous melanoma (CM), MM …

This review presents the main challenges encountered when diagnosing unusual variants of
malignant melanoma with the aim of raising awareness to allow application of the most …

Purpose Due to the rarity and the variety of histological types of sinonasal cancers, there is a
paucity of data regarding strategy for their optimal treatment. Generally, outcomes of …

PRAME (PReferentially expressed Antigen in MElanoma), a cancer-testis antigen expressed
in normal and neoplastic tissues with several functions, proved to be a useful diagnostic tool …

Background We report phase 1b data from patients enrolled in the JAVELIN Solid Tumor
clinical trial (NCT01772004) with unresectable stage IIIC or IV melanoma that had …

Critical appraisal of the available literature for the treatment of canine oral malignant
melanoma (OMM) is lacking. This critical review aimed to evaluate the current literature and …

The updated edition of The World Health Organization Classification of Tumours of the Head
and Neck includes discussions on mucosal melanoma of both the sinonasal and oral cavity …