Intermittent fasting (IF) is an eating pattern in which individuals go extended periods with
little or no energy intake after consuming regular food in intervening periods. IF has several …

Fisetin, a natural flavonoid, possesses numerous biological activities that have been
extensively studied in various diseases. When it comes to cancer, fisetin exhibits a range of …

The aim of the present study was to provide a comprehensive characterization of whole
genome DNA methylation patterns in replicative and ionizing irradiation-or doxorubicin …

The brain endothelial cell (BEC) glycocalyx (ecGCx) is a BEC surface coating consisting of a
complex interwoven polysaccharide (sweet husk) mesh-like network of membrane-bound …

Cellular senescence (CS) is a permanent arrest of cell growth and exit of the cell cycle. It is
an important tumor suppression mechanism and has a key role in wound healing, tissue …

Alzheimer's disease (AD) is one of the major worldwide causes of dementia that is
characterized by irreversible decline in learning, memory loss, and behavioral impairments …

Objective Adipose tissue (AT) senescence is associated with AT dysfunction in rodents, but
little is known about human AT senescence. The study goal was to define the distribution of …

Background: The existence and contribution of microglia with senescent-like alterations in
the pathogenesis of age-related neurodegenerative diseases like Alzheimer's disease (AD) …

An increase in nicotinamide adenine dinucleotide (NAD+) levels alleviates age-related
disease progression and promotes healthy life expectancy. Several studies have …

Senescent cell number increases with age in different tissues, leading to greater senescent
cell load, proinflammatory stress, and tissue dysfunction. In the current study, we tested the …