Background—It is recognized that inflammation is an underlying cause of dry eye disease
(DED), with cytokine release involved. We systematically reviewed literature with meta …

Purpose To assess long-term cumulative treatment effects of intense pulsed light (IPL)
therapy in meibomian gland dysfunction (MGD). Methods Eighty-seven symptomatic …

Purpose To evaluate demographic and lifestyle factors associated with aqueous deficient
and evaporative dry eye disease. Methods A total of 1125 general public visitors (707 …

Abstract In December 2010 and January 2012, 3% diquafosol sodium ophthalmic solution
and 2% rebamipide ophthalmic suspension, respectively, appeared first in Japan as …

Ocular allergy (OA) and dry eye disease (DED) are the most common ocular surface
disorders with a potential severe impact on the patient's quality of life. OA and DED may …

The human tear film is at the interface between the ocular surface and the external
environment. Although investigation has been hindered by its small volume, improvements …

Mucins are key actors in tear film quality and tear film stability. Alteration of membrane-
bound mucin expression on corneal and conjunctival epithelial cells and/or gel-forming …

Background Dry eye disease (DED) is a common cause of ocular pain and discomfort. Dry
eye disease (DED) stems from a loss‐of‐tear film homeostasis and is frequently seen in …

Background Dry eye disease (DED) is among the most prevalent ophthalmic conditions but
is often underdiagnosed and mistreated. Antibiotics are regularly used to treat DED caused …

Using metagenomics, continuing evidence has elicited how intestinal microbiota trigger
distant autoimmunity. Sjögren's syndrome (SS) is an autoimmune disease that affects the …