Ocular surface microbiota in diabetic patients with dry eye disease

Z Zhang, X Zou, W Xue, P Zhang… - … & visual science, 2021 - iovs.arvojournals.org
Purpose: To investigate the ocular surface (OS) commensal bacteria profiles of patients with
diabetes mellitus (DM) and dry eye disease (DED). Methods: In the present study, subjects …

[HTML][HTML] A phase 3, randomized, double-masked study of OTX-101 ophthalmic solution 0.09% in the treatment of dry eye disease

DF Goldberg, RP Malhotra, BA Schechter, A Justice… - Ophthalmology, 2019 - Elsevier
Purpose To evaluate the safety and efficacy of OTX-101, a novel aqueous nanomicellar
formulation of cyclosporine (0.09%), in the treatment of patients with dry eye disease (DED) …

Oxidative and antioxidative stress markers in dry eye disease: A systematic review and meta‐analysis

V Navel, V Sapin, F Henrioux, L Blanchon… - Acta …, 2022 - Wiley Online Library
Purpose To conduct a systematic review and meta‐analysis on the levels of oxidative stress
markers and antioxidants in dry eye disease (DED) compared with healthy subject. Method …

Blue light phototoxicity toward human corneal and conjunctival epithelial cells in basal and hyperosmolar conditions

V Marek, S Mélik-Parsadaniantz, T Villette… - Free Radical Biology …, 2018 - Elsevier
Aims The ocular surface is the very first barrier between the visual system and external
environment. It protects the eye from the exposure to various light sources that significantly …

Dry eye disease: what is the role of vitamin D?

M Rolando, S Barabino - International Journal of Molecular Sciences, 2023 - mdpi.com
Dry eye disease (DED) is a multifactorial condition resulting from reduced tear secretion
from the lacrimal glands, increased tear water evaporation or the production of poor-quality …

Therapeutic benefits of blinking exercises in dry eye disease

AD Kim, A Muntz, J Lee, MTM Wang… - Contact Lens and Anterior …, 2021 - Elsevier
Purpose Dry eye disease (DED) is an important public health concern given its increasing
prevalence and impact on patient quality of life. Blinking frequency and completeness are …

Impact of air pollution on the ocular surface and tear cytokine levels: a multicenter prospective cohort study

R Hao, M Zhang, L Zhao, Y Liu, M Sun, J Dong… - Frontiers in …, 2022 - frontiersin.org
Purpose To assess air pollution-induced changes on ocular surface and tear cytokine levels.
Methods As a prospective multicenter cohort study, 387 dry eye disease (DED) participants …

Dry eye disease and blinking behaviors: A narrative review of methodologies for measuring blink dynamics and inducing blink response

A Oganov, G Yazdanpanah, S Jabbehdari… - The Ocular Surface, 2023 - Elsevier
Dry eye disease (DED) is a leading cause of ophthalmology clinical encounters with
prevalence ranging from 8.7% to 64% in various populations. Blinking is an endogenous …

Ocular surface pain: a narrative review

D Mehra, NK Cohen, A Galor - Ophthalmology and therapy, 2020 - Springer
Ocular surface pain is a frequent cause of visits to an eye care provider and has a
substantial impact on healthcare cost, yet a complete understanding of its causative factors …

Increased systemic immune-inflammation index levels in patients with dry eye disease

D Ozarslan Ozcan, BE Kurtul, SC Ozcan… - Ocular immunology and …, 2022 - Taylor & Francis
Purpose To evaluate the systemic immune-inflammation index (SII) levels, neutrophil-to-
lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in patients with dry eye …