In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Our understanding of the still unfolding severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic would have been extremely limited without the study of the …

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, multiple severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …

Although mRNA vaccine efficacy against severe coronavirus disease 2019 remains high,
variant emergence has prompted booster immunizations. However, the effects of repeated …

The emergence of Omicron sublineages impacts the therapeutic efficacy of anti-severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monoclonal antibodies (mAbs) …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hybrid immunity is more
protective than vaccination or previous infection alone. To investigate the kinetics of spike …

Members of the coronaviridae family are endemic to human populations and have caused
several epidemics and pandemics in recent history. In this review, we will discuss the …

SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …