[HTML][HTML] Pathophysiology and clinical management of coronavirus disease (COVID-19): a mini-review

Y Zhu, L Sharma, D Chang - Frontiers in Immunology, 2023 - frontiersin.org
An unprecedented global pandemic caused by a novel coronavirus named SARS-CoV-2
has created a severe healthcare threat and become one of the biggest challenges to human …

Comparative efficacy and safety of nirmatrelvir/ritonavir and molnupiravir for COVID‐19: A systematic review and meta‐analysis

B Amani, A Akbarzadeh, B Amani… - Journal of Medical …, 2023 - Wiley Online Library
This study aimed to compare the efficacy and safety of nirmatrelvir/ritonavir (Paxlovid) with
molnupiravir in the treatment of coronavirus disease 2019 (COVID‐19). To end this …

Efficacy and safety of molnupiravir treatment for COVID-19: a systematic review and meta-analysis of randomized controlled trials

F Tian, Q Feng, Z Chen - International Journal of Antimicrobial Agents, 2023 - Elsevier
Introduction There are currently some differences in the research results of molnupiravir.
This study aimed to evaluate the efficacy and safety of molnupiravir in the treatment of …

[HTML][HTML] Efficacy of Molnupiravir for the treatment of mild or moderate COVID-19 in adults: a meta-analysis

K Benaicha, RR Khenhrani, M Veer, S Devi… - Cureus, 2023 - ncbi.nlm.nih.gov
The aim of this meta-analysis is to evaluate the efficacy of molnupiravir among mild or
moderate COVID-19 patients. This meta-analysis was reported according to the guidelines …

[HTML][HTML] Development and Validation of a High-Performance Liquid Chromatography with Tandem Mass Spectrometry (HPLC-MS/MS) Method for Quantification of …

T Komarov, P Karnakova, O Archakova… - Biomedicines, 2023 - mdpi.com
Molnupiravir is an antiviral drug against viral RNA polymerase activity approved by the FDA
for the treatment of COVID-19, which is metabolized to β-D-N4-hydroxycytidine (NHC) in …

Pulmonary recovery after COVID-19–a review

T Sonnweber, S Birgit, G Weiss… - Expert Review of …, 2023 - Taylor & Francis
Introduction COVID-19 is caused by infection with the severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2). As the respiratory tract is the primary site of infection and …

[HTML][HTML] Microfluidic strategies for biomimetic lung chip establishment and SARS-CoV2 study

H Wang, T Wen, W Zhu, K Li, X Gong, Z Li - Materials Today Bio, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), characterized by its high
fatality rate and contagious nature, has led to significant morbidity and mortality worldwide …

Comparative docking and molecular dynamics studies of molnupiravir (EIDD-2801): implications for novel mechanisms of action on influenza and SARS-CoV-2 …

ES Istifli, N Okumus, C Sarikurkcu… - Journal of …, 2023 - Taylor & Francis
Abstract Molnupiravir (EIDD-2801)(MLN) is an oral antiviral drug for COVID-19 treatment,
being integrated into viral RNA through RNA-dependent RNA polymerase (RdRp). Upon …

Molnupiravir's real-world effectiveness in COVID-19 outpatients at high risk of severe disease: a single-center study

II Gmizic, A Barac, N Todorovic, M Sabanovic… - The Journal of Infection …, 2024 - jidc.org
Introduction: The coronavirus disease 2019 (COVID-19) pandemic started in March 2020.
Since then, there has been an urgent need for effective therapeutic methods to manage the …

Molnupiravir's real-world effectiveness in COVID-19 non-hospitalized patients at high risk of severe disease: a single-center study

I Gmizic, N Todorovic, M Sabanovic, N Kekic… - medRxiv, 2023 - medrxiv.org
Objective To assess the real-world effectiveness of molnupiravir (MOL) in reducing the need
for hospitalization in at-risk, non-hospitalized patients with confirmed COVID-19. Methods A …