[HTML][HTML] Causal relationship between immune cells and prostate cancer: a Mendelian randomization study

Z Ye, X Deng, J Zhang, R Shao, C Song… - Frontiers in Cell and …, 2024 - frontiersin.org
Introduction: Despite the abundance of research indicating the participation of immune cells
in prostate cancer development, establishing a definitive cause-and-effect relationship has …

[HTML][HTML] Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2

Y Zhu, J Li, P Zhang, B Peng, C Li, Y Ming, H Liu - PeerJ, 2023 - peerj.com
Background During hepatic ischemia-reperfusion injury, the excessive release of
inflammatory cytokines can activate the intracellular signal transduction cascade to induce …

Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis

J Lun, Y Zhang, M Yu, W Zhai, L Zhu, H Liu, J Guo… - Cancer Letters, 2024 - Elsevier
Circular RNAs (circRNAs) have been implicated in cancer development. However, their
regulation, function, and underlying mechanisms of action remain unclear. We found that …

Deciphering a GPCR-lncrna-miRNA nexus: Identification of an aberrant therapeutic target in ovarian cancer

JH Ha, R Radhakrishnan, R Nadhan… - Cancer Letters, 2024 - Elsevier
Ovarian cancer ranks as a leading cause of mortality among gynecological malignancies,
primarily due to the lack of early diagnostic tools, effective targeted therapy, and clear …

CircUGGT2 facilitates progression and cisplatin resistance of bladder cancer through nonhomologous end-joining pathway

F Lyu, S Huang, Z Yan, Q He, C Liu, L Cheng, Y Cong… - Cellular …, 2024 - Elsevier
The development of resistance to cisplatin (CDDP) in bladder cancer presents a notable
obstacle, with indications pointing to the substantial role of circular RNAs (circRNAs) in this …

Prognostic value of lncRNA LINC01018 in prostate cancer by regulating miR-182-5p (The role of LINC01018 in prostate cancer)

W Luo, T Li, Q Song, L Zhang, M Cao - Nucleosides, Nucleotides & …, 2023 - Taylor & Francis
LncRNAs are abnormally expressed in a variety of cancers and play unique roles in therapy.
Based on this, the prognostic value of lncRNA LINC01018 in prostate cancer was discussed …

Cellular senescence: A potential mode of circular RNAs regulating prostate cancer

Y Li, A Fan, Y Zhang, Z Guo, W Meng… - MedComm …, 2023 - Wiley Online Library
Cellular senescence is a state characterized by permanent cell cycle stoppage, which has
long been viewed as a protective mechanism against neoplasia. However, accumulating …

Study on the mechanism of miR-361-5p regulation of androgen receptor in castration-resistant transformation of prostate cancer

P Zhang, X Yin, X Li, M Zang, Q Liang, Z Zhang, L Liu… - 2024 - researchsquare.com
Prostate cancer has become one of the most common tumors endangering men's health. At
present, the main clinical treatments for prostate tumors are surgery, radiotherapy, endocrine …

Trillin-Mediated Inhibition of NF-κB/COX-2 Signaling Pathways through Upregulation of miR-145-5p Targeting MAP3K11 in Castration-Resistant Prostate Cancer

Y Wang, Y Peng, W Hao, X Gao, P Liang, H Zhao… - 2024 - researchsquare.com
Purpose Prostate cancer remains a leading cause of cancer-related deaths among men
worldwide, driving the need for innovative therapeutic avenues. Despite preliminary …

Trillin Inhibit NF-κB/COX-2/MAPK Signaling Pathways Through Upregulation of miR-145-5p in Castration-Resistant Prostate Cancer

Y Wang, Y Peng, W Hao, X Gao, P Liang, H Zhao… - papers.ssrn.com
Prostate cancer is a common malignancy in men, which transforms into castration-resistant
prostate cancer (CRPC) after androgen deprivation therapy (ADT). However, the optimal …