The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Spontaneous preterm birth: Involvement of multiple feto-maternal tissues and organ systems, differing mechanisms, and pathways
MS Vidal Jr, RCV Lintao, MEL Severino… - Frontiers in …, 2022 - frontiersin.org
Survivors of preterm birth struggle with multitudes of disabilities due to improper in utero
programming of various tissues and organ systems contributing to adult-onset diseases at a …
programming of various tissues and organ systems contributing to adult-onset diseases at a …
[HTML][HTML] Evidence that intra-amniotic infections are often the result of an ascending invasion–a molecular microbiological study
Background Microbial invasion of the amniotic cavity resulting in intra-amniotic infection is
associated with obstetrical complications such as preterm labor with intact or ruptured …
associated with obstetrical complications such as preterm labor with intact or ruptured …
Maternal and fetal T cells in term pregnancy and preterm labor
Pregnancy is a state of immunological balance during which the mother and the developing
fetus must tolerate each other while maintaining sufficient immunocompetence to ward off …
fetus must tolerate each other while maintaining sufficient immunocompetence to ward off …
[HTML][HTML] Fetal and maternal NLRP3 signaling is required for preterm labor and birth
Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. One of
every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by …
every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by …
Sneathia: an emerging pathogen in female reproductive disease and adverse perinatal outcomes
Sneathia is an emerging pathogen implicated in adverse reproductive and perinatal
outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes …
outcomes. Although scarce, recent data suggest that vaginally residing Sneathia becomes …
Cellular immune responses in amniotic fluid of women with preterm prelabor rupture of membranes
Background Preterm birth is the leading cause of perinatal morbidity and mortality. Preterm
prelabor rupture of membranes (pPROM) occurs in 30% of preterm births; thus, this …
prelabor rupture of membranes (pPROM) occurs in 30% of preterm births; thus, this …
The alarmin interleukin-1α causes preterm birth through the NLRP3 inflammasome
Sterile intra-amniotic inflammation is a clinical condition frequently observed in women with
preterm labor and birth, the leading cause of neonatal morbidity and mortality worldwide …
preterm labor and birth, the leading cause of neonatal morbidity and mortality worldwide …
Does the amniotic fluid of mice contain a viable microbiota?
The existence of an amniotic fluid microbiota (ie, a viable microbial community) in mammals
is controversial. Its existence would require a fundamental reconsideration of fetal in utero …
is controversial. Its existence would require a fundamental reconsideration of fetal in utero …
A single-cell atlas of murine reproductive tissues during preterm labor
Preterm birth, the leading cause of perinatal morbidity and mortality worldwide, frequently
results from the syndrome of preterm labor. The best-established causal link to preterm labor …
results from the syndrome of preterm labor. The best-established causal link to preterm labor …