Conjugated linoleic acid isomers reduce cholesterol accumulation in acetylated LDL-induced mouse RAW264. 7 macrophage-derived foam cells

R Ringseis, G Wen, D Saal, K Eder - Lipids, 2008 - Springer
Synthetic activators of peroxisome proliferator-activated receptors (PPAR)-α and-γ are
capable of reducing macrophage foam cell cholesterol accumulation through the activation …

Lipid metabolism impairment in human gliomas: expression of peroxisomal proteins in human gliomas at different grades of malignancy

E Benedetti, R Galzio, G Laurenti… - International …, 2010 - journals.sagepub.com
Gliomas are histologically graded by cellularity, cytological atypia, necrosis, mitotic figures,
and vascular proliferation, features associated with biologically aggressive behaviour …

A PPARs cross‐talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis

AV Leisewitz, CR Urrutia, GR Martinez… - Journal of cellular …, 2008 - Wiley Online Library
Peroxisome proliferator activated receptors (PPARs, α, β/δ, γ) control lipid homeostasis and
differentiation in various tissues and tumor cells. PPARβ and PPARγ increase …

Global and Regional DNA methylation silencing of PPARγ Associated with Glioblastoma Multiforme Pathogenesis

E Babaeenezhad, M Moradi Sarabi… - Molecular Biology …, 2023 - Springer
Background The relationship between peroxisome proliferator-activated receptor gamma
(PPARγ) expression level and epigenetic modifications occurring in glioblastoma multiforme …

t-10, c-12 CLA Dietary Supplementation Inhibits Atherosclerotic Lesion Development Despite Adverse Cardiovascular and Hepatic Metabolic Marker Profiles

PL Mitchell, TK Karakach, DL Currie, RS McLeod - PLoS One, 2012 - journals.plos.org
Animal and human studies have indicated that fatty acids such as the conjugated linoleic
acids (CLA) found in milk could potentially alter the risk of developing metabolic disorders …

Conjugated linoleic acid: a functional nutrient in the different pathophysiological components of the metabolic syndrome?

S Toomey, J McMonagle… - Current Opinion in Clinical …, 2006 - journals.lww.com
Conjugated linoleic acid: a functional nutrient in the diffe... : Current Opinion in Clinical
Nutrition & Metabolic Care Conjugated linoleic acid: a functional nutrient in the different …

[HTML][HTML] Os efeitos do ácido linoléico conjugado no metabolismo animal: avanço das pesquisas e perspectivas para o futuro

LF Santos-Zago, AP Botelho, AC Oliveira - Revista de Nutrição, 2008 - SciELO Brasil
Realizou-se uma revisão sistemática, sem restrição de data, sobre os efeitos fisiológicos do
ácido linoléico conjugado sobre a regressão da carcinogênese, o estresse oxidativo, o …

PPARs in human neuroepithelial tumors: PPAR ligands as anticancer therapies for the most common human neuroepithelial tumors

E Benedetti, R Galzio, BD′ Angelo, MP Ceru… - PPAR …, 2010 - Wiley Online Library
Neuroepithelial tumors represent a heterogeneous class of human tumors including
benignant and malignant tumors. The incidence of central nervous system neoplasms …

Trans‐10, cis 12‐Conjugated Linoleic Acid‐Induced Milk Fat Depression Is Associated with Inhibition of PPARγ Signaling and Inflammation in Murine Mammary …

AKG Kadegowda, MJ Khan, LS Piperova… - Journal of …, 2013 - Wiley Online Library
Exogenous trans‐10, cis‐12‐CLA (CLA) reduces lipid synthesis in murine adipose and
mammary (MG) tissues. However, genomewide alterations in MG and liver (LIV) associated …

Antiproliferative effect of conjugated linoleic acid in caco-2 cells: involvement of PPARγ and APC/β-catenin pathways

F Bozzo, C Bocca, S Colombatto, A Miglietta - Chemico-biological …, 2007 - Elsevier
Conjugated linoleic acid (CLA), a naturally occurring substance in food sources, occurs as
mixtures of positional and geometrical isomers of octadecadienoate (18: 2), and may inhibit …