Cholangiocarcinoma 2020: the next horizon in mechanisms and management

JM Banales, JJG Marin, A Lamarca… - Nature reviews …, 2020 - nature.com
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

New challenges in the management of cholangiocarcinoma: the role of liver transplantation, locoregional therapies, and systemic therapy

E Mauro, J Ferrer-Fàbrega, T Sauri, A Soler, A Cobo… - Cancers, 2023 - mdpi.com
Simple Summary Cholangiocarcinoma (CCA) is a highly lethal neoplasia, which incidence
has steadily increased in the last years. Although surgical resection remains the cornerstone …

EASL Clinical Practice Guidelines on sclerosing cholangitis

O Chazouilleres, U Beuers, A Bergquist, TH Karlsen… - Journal of …, 2022 - Elsevier
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

Liver transplantation as a new standard of care in patients with perihilar cholangiocarcinoma? Results from an international benchmark study

E Breuer, M Mueller, MB Doyle, L Yang… - Annals of …, 2022 - journals.lww.com
Objective: To define benchmark values for liver transplantation (LT) in patients with perihilar
cholangiocarcinoma (PHC) enabling unbiased comparisons. Background: Transplantation …

The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression

N Liu, J Zhang, W Chen, W Ma, T Wu - Journal of Experimental & Clinical …, 2023 - Springer
Abstract Background RNA N6-Methyladenosine (m6A) modification is implicated in the
progression of human cancers including cholangiocarcinoma (CCA). METTL16 is recently …

Hypoxia-induced SKA3 promoted cholangiocarcinoma progression and chemoresistance by enhancing fatty acid synthesis via the regulation of PAR-dependent HIF …

Y Chen, X Xu, Y Wang, Y Zhang, T Zhou… - Journal of Experimental …, 2023 - Springer
Background Spindle and kinetochore-associated complex subunit 3 (SKA3) plays an
important role in cell proliferation by regulating the separation of chromosomes and their …

Liver transplantation for intrahepatic cholangiocarcinoma: a meta-analysis and meta-regression of survival rates

IA Ziogas, D Giannis, KP Economopoulos… - …, 2021 - journals.lww.com
Background. Intrahepatic cholangiocarcinoma (iCCA) is a contraindication to liver
transplantation in most centers worldwide. Therefore, only a few such cases have been …

British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma

SM Rushbrook, TJ Kendall, Y Zen, R Albazaz… - Gut, 2024 - gut.bmj.com
These guidelines for the diagnosis and management of cholangiocarcinoma (CCA) were
commissioned by the British Society of Gastroenterology liver section. The guideline writing …

[HTML][HTML] Liver transplantation in the management of cholangiocarcinoma: Evolution and contemporary advances

A Borakati, F Froghi, RH Bhogal… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) is an aggressive malignancy arising from the biliary epithelium.
It may occur at any location along the biliary tree with the perihilar area being the most …

Current perspectives on the surgical management of perihilar cholangiocarcinoma

DB Hewitt, ZJ Brown, TM Pawlik - Cancers, 2022 - mdpi.com
Simple Summary Perihilar cholangiocarcinoma is a rare disease with generally poor
outcomes. Complete surgical resection remains the only chance at long-term survival …