Dynamic chromatin remodeling underlies many, if not all, DNA-templated biological
processes, including gene transcription; DNA replication and repair; chromosome …

Histone methylation is a dynamic process that participates in a diverse array of cellular
processes and has been found to associate with cancer. Recently, several histone …

Post-translational modifications, such as acetylation or phosphorylation, play a crucial role in
the regulation of gene transcription in eukaryotes. Different subtypes of histone acetyl …

Researches on the microbiome have been actively conducted worldwide and the results
have shown human gut bacterial environment significantly impacts on immune system …

Defining the protein factors that directly recognize post-translational, covalent histone
modifications is essential toward understanding the impact of these chromatin" marks" on …

The development of cancer is driven by the accumulation of scores of alterations affecting
the structure and function of the genome. Equally important in this process are genetic …

Epigenetic alterations are associated with normal biological processes such as aging or
differentiation. Changes in global epigenetic signatures, together with genetic alterations …

The role of epigenetics in aging and age-related diseases is a key issue in molecular
physiology and medicine because certain epigenetic factors are thought to mediate, at least …

While the field of cancer genetics has enjoyed a great deal of attention among cancer
researchers in the last few decades, the appreciation of cancer epigenetics is more recent …

Several aspects of epigenetics are strongly linked to non-coding RNAs, especially small
RNAs that can direct the cytosine methylation and histone modifications that are implicated …