Inheritance of paternal lifestyles and exposures through sperm DNA methylation

KW Greeson, KMS Crow, RC Edenfield… - Nature Reviews …, 2023 - nature.com
Many different lifestyle factors and chemicals present in the environment are a threat to the
reproductive tracts of humans. The potential for parental preconception exposure to alter …

Epigenomic and other evidence for cannabis-induced aging contextualized in a synthetic epidemiologic overview of cannabinoid-related teratogenesis and …

AS Reece, GK Hulse - … Journal of Environmental Research and Public …, 2022 - mdpi.com
Background: Twelve separate streams of empirical data make a strong case for cannabis-
induced accelerated aging including hormonal, mitochondriopathic, cardiovascular …

Genomic map of candidate human imprint control regions: the imprintome

DD Jima, DA Skaar, A Planchart, A Motsinger-Reif… - Epigenetics, 2022 - Taylor & Francis
Imprinted genes–critical for growth, metabolism, and neuronal function–are expressed from
one parental allele. Parent-of-origin-dependent CpG methylation regulates this expression …

Sperm DNA methylation alterations from cannabis extract exposure are evident in offspring

R Schrott, JL Modliszewski, AB Hawkey… - Epigenetics & …, 2022 - Springer
Background Cannabis legalization is expanding and men are the predominant users. We
have limited knowledge about how cannabis impacts sperm and whether the effects are …

Epigenetic changes in sperm are associated with paternal and child quantitative autistic traits in an autism-enriched cohort

JI Feinberg, R Schrott, C Ladd-Acosta… - Molecular …, 2024 - nature.com
There is a need to consider paternal contributions to autism spectrum disorder (ASD) more
strongly. Autism etiology is complex, and heritability is not explained by genetics alone …

Cannabinoid and substance relationships of European congenital anomaly patterns: a space-time panel regression and causal inferential study

AS Reece, GK Hulse - Environmental Epigenetics, 2022 - academic.oup.com
Abstract With reports from Australia, Canada, USA, Hawaii and Colorado documenting a link
between cannabis and congenital anomalies (CAs), this relationship was investigated in …

Novel Insights into Potential Cannabis-Related Cancerogenesis from Recent Key Whole Epigenome Screen of Cannabis Dependence and Withdrawal …

AS Reece, GK Hulse - Genes, 2022 - mdpi.com
Whilst the cannabis-cancer link has been traditionally described as controversial recent
whole nation and whole continent studies have demonstrated that well documented …

Geospatiotemporal and causal inference study of cannabis and other drugs as risk factors for female breast cancer USA 2003–2017

AS Reece, GK Hulse - Environmental Epigenetics, 2022 - academic.oup.com
Breast cancer (BC) is the commonest human cancer and its incidence (BC incidence, BCI) is
rising worldwide. Whilst both tobacco and alcohol have been linked to BCI genotoxic …

Cannabis-and Substance-Related Carcinogenesis in Europe: A Lagged Causal Inferential Panel Regression Study

AS Reece, K Bennett, GK Hulse - Journal of Xenobiotics, 2023 - mdpi.com
Recent European data facilitate an epidemiological investigation of the controversial
cannabis–cancer relationship. Of particular concern were prior findings associating high …

European epidemiological patterns of cannabis-and substance-related body wall congenital anomalies: geospatiotemporal and causal inferential study

AS Reece, GK Hulse - … Journal of Environmental Research and Public …, 2022 - mdpi.com
As body wall congenital anomalies (BWCAs) have a long history of being associated with
prenatal or community cannabis exposure (CCE), it was of interest to investigate these …