Mechanisms of B-Myb oncogenicity in ovarian cancer
AN Iness - 2018 - scholarscompass.vcu.edu
High expression of B-Myb (encoded by MYBL2), an oncogenic transcription factor, is
associated with cell cycle deregulation and poor prognosis in several cancers, including …
associated with cell cycle deregulation and poor prognosis in several cancers, including …
RNF169 and RNF168 novel substrates of DYRK1A: connecting DYRK1A to DNA-damage repair
JM Roewenstrunk - 2018 - tdx.cat
Gene dosage alterations of the kinase DYRK1A are linked to disease in humans. To better
understand DYRK1A activities an interactome analysis was performed. RNF169, an E3 …
understand DYRK1A activities an interactome analysis was performed. RNF169, an E3 …
[PDF][PDF] CMGC kinases and Cancer
S Keskitalo - Academic dissertation. Helsinki: Hansaprint, 2017 - helda.helsinki.fi
II. Turunen M*, Spaeth JM*, Keskitalo S, Park MJ, Kivioja T, Clark AD, Mäkinen N, Gao F,
Palin K, Nurkkala H, Vähärautio A, Aavikko M, Kämpjärvi K, Vahteristo P, Kim CA, Aaltonen …
Palin K, Nurkkala H, Vähärautio A, Aavikko M, Kämpjärvi K, Vahteristo P, Kim CA, Aaltonen …
Rational Design and Identification of Harmine-Inspired, N-Heterocyclic DYRK1A Inhibitors Employing a Functional Genomic in vivo Drosophila Model System
Deregulation of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A)
plays a significant role in developmental brain defects, early-onset neurodegeneration …
plays a significant role in developmental brain defects, early-onset neurodegeneration …
Modulating Endolysosomal Trafficking as Therapeutic Strategy Against Colorectal Cancer
NA Hussein - 2021 - search.proquest.com
The development of resistance to apoptosis-inducing chemotherapeutic compounds is a
major challenge associated with the treatment of solid malignant tumors. An example of …
major challenge associated with the treatment of solid malignant tumors. An example of …
Modifications fonctionnelles en position C2 des 8-alkylthiazolo [5, 4-f] quinazolin-9 (8H)-ones et stratégie d'extension de fragment pour la synthèse d'inhibiteurs de …
F Couly - 2018 - theses.hal.science
Les effets du dérèglement de l'expression des protéines kinases DYRK (Dual-specificity
tyrosine phosphorylation-regulated kinase) et plus particulièrement de DYRK1A sont …
tyrosine phosphorylation-regulated kinase) et plus particulièrement de DYRK1A sont …
7-Iodo-1H-indole-3-carbonitrile
R Meine, H Falke, J Kötz, SI Schweda, C Kunick - Molbank, 2015 - mdpi.com
The title compound was prepared by a Friedel–Crafts acylation-oxime synthesis-
decarboxylation/dehydration sequence starting from commercially available 7-iodoindole …
decarboxylation/dehydration sequence starting from commercially available 7-iodoindole …
Characterization of the TSC/DYRK1A Interaction
S Joshi - 2020 - scholarscompass.vcu.edu
The Tuberous sclerosis complex (TSC) includes TSC1, TSC2 and the TBC1D7 subunits that
together function as a principal inhibitor of the mTOR protein kinase complex 1 (mTORC1) …
together function as a principal inhibitor of the mTOR protein kinase complex 1 (mTORC1) …
[PDF][PDF] Design, synthesis and characterisation of tool compounds to define the roles of Serine racemase and Dual-specificity tyrosine phosphorylation-regulated kinase …
SH Henderson - 2019 - sussex.figshare.com
A University of Sussex PhD thesis Available online via Sussex Research Online: http://sro.sussex.ac.uk/
This Page 1 A University of Sussex PhD thesis Available online via Sussex Research Online …
This Page 1 A University of Sussex PhD thesis Available online via Sussex Research Online …