Atherosclerosis can be regarded as a chronic inflammatory state, in which macrophages
play different and important roles. Phagocytic proinflammatory cells populate growing …

Toll-like receptors (TLR) mediate infection-induced inflammation and sterile inflammation by
endogenous molecules. Among the TLR family, TLR4 is the best understood. However …

Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

Microbes or danger signals trigger inflammasome sensors, which induce polymerization of
the adaptor ASC and the assembly of ASC specks. ASC specks recruit and activate caspase …

Scavenger receptors belong to a superfamily of proteins that are structurally heterogeneous
and encompass the miscellaneous group of transmembrane proteins and soluble secretory …

Atherosclerosis is considered a chronic inflammatory disease of the arterial wall. Recently,
compelling evidence has arisen for the role of monocytes and neutrophils and a particular …

The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant
stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis …

Phagocytosis is a remarkably complex and versatile process: it contributes to innate
immunity through the ingestion and elimination of pathogens, while also being central to …

Neuroinflammation is a common feature in neurodegenerative diseases and strategies to
modulate neuroinflammatory processes are increasingly considered as therapeutic options …

Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most
common cause of dementia. Deposition of amyloid‐β (Aβ) remains a hallmark feature of the …