Interpretation and impact of real-world clinical data for the practicing clinician

L Blonde, K Khunti, SB Harris, C Meizinger… - Advances in …, 2018 - Springer
Real-world studies have become increasingly important in providing evidence of treatment
effectiveness in clinical practice. While randomized clinical trials (RCTs) are the “gold …

Oxidative stress-mediated beta cell death and dysfunction as a target for diabetes management

S Dinić, J Arambašić Jovanović, A Uskoković… - Frontiers in …, 2022 - frontiersin.org
The biggest drawback of a current diabetes therapy is the treatment of the consequences not
the cause of the disease. Regardless of the diabetes type, preservation and recovery of …

Сахарный диабет в Российской Федерации: распространенность, заболеваемость, смертность, параметры углеводного обмена и структура …

ИИ Дедов, МВ Шестакова, ОК Викулова… - Сахарный …, 2018 - cyberleninka.ru
ОБОСНОВАНИЕ. Колоссальный социальный ущерб, связанный с высокой
распространенностью сахарного диабета (СД), обусловливает государственную …

Association of real-time continuous glucose monitoring with glycemic control and acute metabolic events among patients with insulin-treated diabetes

AJ Karter, MM Parker, HH Moffet, LK Gilliam, R Dlott - Jama, 2021 - jamanetwork.com
Importance Continuous glucose monitoring (CGM) is recommended for patients with type 1
diabetes; observational evidence for CGM in patients with insulin-treated type 2 diabetes is …

Primary prevention of cardiovascular and heart failure events with SGLT2 inhibitors, GLP-1 receptor agonists, and their combination in type 2 diabetes

AK Wright, MJ Carr, E Kontopantelis… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE To assess associations between current use of sodium–glucose cotransporter 2
inhibitors (SGLT2is), glucagon-like peptide 1 receptor agonists (GLP-1RAs), and their …

Glycemic outcomes in adults with T1D are impacted more by continuous glucose monitoring than by insulin delivery method: 3 years of follow-up from the COMISAIR …

J Šoupal, L Petruželková, G Grunberger… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE This study assessed the clinical impact of four treatment strategies in adults with
type 1 diabetes (T1D): real-time continuous glucose monitoring (rtCGM) with multiple daily …

[HTML][HTML] Diabetes mellitus in Russian Federation: prevalence, morbidity, mortality, parameters of glycaemic control and structure of glucose lowering therapy according …

II Dedov, MV Shestakova, OK Vikulova… - Diabetes …, 2018 - dia-endojournals.ru
BACKGROUND: The enormous social lesion caused by high prevalence of diabetes
mellitus (DM) determines the state importance of clinical and epidemiological monitoring …

[HTML][HTML] My diabetes coach, a mobile app–based interactive conversational agent to support type 2 diabetes self-management: randomized effectiveness …

E Gong, S Baptista, A Russell, P Scuffham… - Journal of medical …, 2020 - jmir.org
Background Delivering self-management support to people with type 2 diabetes mellitus is
essential to reduce the health system burden and to empower people with the skills …

Precision medicine in the management of type 2 diabetes

AL Gloyn, DJ Drucker - The lancet Diabetes & endocrinology, 2018 - thelancet.com
The study of type 2 diabetes has been driven by advances in human genetics, epigenetics,
biomarkers, mechanistic studies, and large clinical trials, enabling new insights into disease …

Central nervous system control of glucose homeostasis: a therapeutic target for type 2 diabetes?

Z Mirzadeh, CL Faber… - Annual review of …, 2022 - annualreviews.org
Historically, pancreatic islet beta cells have been viewed as principal regulators of glycemia,
with type 2 diabetes (T2D) resulting when insulin secretion fails to compensate for …