[PDF][PDF] Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity

D Batlle, V Monteil, E Garreta, L Hassler, J Wysocki… - Cell, 2022 - cell.com
A recent paper in Cell entitled ''Soluble ACE2-mediated cell entry of SARS-CoV-2 via
interaction with proteins related to the renin-angiotensin system''by Yeung et al.(2021) …

[HTML][HTML] Human induced pluripotent stem cell-derived kidney organoids toward clinical implementations

E Garreta, Z Nauryzgaliyeva, N Montserrat - Current Opinion in Biomedical …, 2021 - Elsevier
The generation of kidney organoids from human pluripotent stem cells (hPSCs) has
represented a relevant scientific achievement in the organoid field. Importantly, hPSC …

Engineering multicellular living systems—A keystone Symposia report

J Cable, P Arlotta, KK Parker, AJ Hughes… - Annals of the New …, 2022 - Wiley Online Library
The ability to engineer complex multicellular systems has enormous potential to inform our
understanding of biological processes and disease and alter the drug development process …

Clinical grade ACE2 effectively inhibits SARS-CoV-2 Omicron infections

V Monteil, D Stephanie, J Klingström, C Thålin… - bioRxiv, 2021 - biorxiv.org
The recent emergence of the SARS-CoV-2 variant Omicron has caused considerable
concern due to reduced vaccine efficacy and escape from neutralizing antibody …