Long COVID: Clinical characteristics, proposed pathogenesis and potential therapeutic targets

G Kenny, L Townsend, S Savinelli… - Frontiers in Molecular …, 2023 - frontiersin.org
The emergence of persistent ill-health in the aftermath of SARS-CoV-2 infection has
presented significant challenges to patients, healthcare workers and researchers. Termed …

Post COVID-19 condition, work ability and occupational changes in a population-based cohort

P Kerksieck, T Ballouz, SR Haile… - The Lancet Regional …, 2023 - thelancet.com
Background Evidence on the impact of post COVID-19 condition (PCC) on work ability is
limited but critical due to its high prevalence among working-age individuals. This study …

Post-acute COVID-19 sequelae in a working population at one year follow-up: a wide range of impacts from an Italian sample

D Buonsenso, MR Gualano, MF Rossi… - International Journal of …, 2022 - mdpi.com
Long COVID-19 is a term used to describe the symptomatic sequelae that develop after
suffering from COVID-19. Very few studies have investigated the impact of COVID-19 …

Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled …

LEM Finnigan, MP Cassar, MJ Koziel, J Pradines… - …, 2023 - thelancet.com
Background 'Long COVID'describes persistent symptoms, commonly fatigue, lasting beyond
12 weeks following SARS-CoV-2 infection. Potential causes include reduced mitochondrial …

Natural history of long-COVID in a nationwide, population cohort study

CE Hastie, DJ Lowe, A McAuley, NL Mills… - Nature …, 2023 - nature.com
Previous studies on the natural history of long-COVID have been few and selective. Without
comparison groups, disease progression cannot be differentiated from symptoms originating …

Functional Recovery of Adults Following Acute COVID-19: A Systematic Review and Meta-Analysis

S Middleton, CV Chalitsios, T Mungale… - Physical …, 2024 - academic.oup.com
Objective This systematic review and meta-analysis aimed to investigate the objective,
functional recovery of patients more than 3 months after acute COVID-19 infection. Methods …

Cognitive and emotional predictors of quality of life and functioning after COVID‐19

M Ariza, N Cano, B Segura, J Bejar… - Annals of clinical …, 2024 - Wiley Online Library
Objective A long‐term decline in health‐related quality of life (HRQoL) has been reported
after coronavirus disease 2019 (COVID‐19). Studies with people with persistent symptoms …

One-year functional decline in COVID-19 and non-COVID-19 critically ill survivors: a prospective study incorporating a pre-ICU status assessment

J Cavalleri, D Treguier, T Deliège, C Gurdebeke… - Healthcare, 2022 - mdpi.com
We aimed to describe the one-year (1-y) functional status of survivors of COVID-19 critical
illness, compared to non-COVID-19 survivors, and compared to their pre-ICU status. Adults …

Return to work and health-related quality of life up to 1 year in patients hospitalized for COVID-19: the CO-FLOW study

LM Bek, JC Berentschot, ME Hellemons, SC Remerie… - BMC medicine, 2023 - Springer
Background Currently, evidence about the long-term consequences of COVID-19 on return
to work and health-related quality of life (HRQoL) is limited. We evaluated return to work and …

Post-acute sequelae of SARS-CoV-2 (PASC) impact quality of life at 6, 12 and 18 months post-infection

ZO Demko, T Yu, SK Mullapudi, MG Varela Heslin… - MedRxiv, 2022 - medrxiv.org
Little data exist on long COVID outcomes beyond one year. In a cohort enrolled with mild-
moderate acute COVID-19, a wide range of symptoms manifest at 6, 12, and 18 months …