Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum
disorder and schizophrenia. Animal models corroborate this link and demonstrate that …

Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

Due to an inability to ethically access developing human brain tissue as well as identify
prospective cases, early-arising neurodevelopmental and cell-specific signatures of …

Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

Stressors ranging from psychogenic/social to neurogenic/injury to systemic/microbial can
impact microglial inflammatory processes, but less is known regarding their effects on …

The brain is increasingly appreciated to be a constantly rewired organ that yields age-
specific behaviors and responses to the environment. Adolescence in particular is a unique …

Prenatal infections have been linked to the development of schizophrenia (SCZ) and other
neurodevelopmental disorders in the offspring, and work in animal models indicates that this …

Maternal immune activation (MIA) during pregnancy is an established environmental risk
factor for schizophrenia. Timing of immune activation exposure as well as sex of the …

In addition to their traditional role as immune sentinels, recent discoveries over the last
decade have shown that microglial functions now include regulation of neuronal/glial cell …

It is widely accepted that narcotic use during pregnancy and specific environmental factors
(eg, maternal immune activation and chronic stress) may increase risk of neuropsychiatric …