Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence
SARS-CoV-2 has infected over 160 million and caused more than 3 million deaths to date.
Most individuals (> 80%) have mild symptoms and recover in the outpatient setting, but …
Most individuals (> 80%) have mild symptoms and recover in the outpatient setting, but …
[HTML][HTML] An overview of the conventional and novel methods employed for SARS-CoV-2 neutralizing antibody measurement
VPC Rocha, HC Quadros, AMS Fernandes… - Viruses, 2023 - mdpi.com
SARS-CoV-2 is the etiological agent of the coronavirus disease-19 (COVID-19) and is
responsible for the pandemic that started in 2020. The virus enters the host cell through the …
responsible for the pandemic that started in 2020. The virus enters the host cell through the …
[HTML][HTML] Vaccination with SARS-CoV-2 spike protein and AS03 adjuvant induces rapid anamnestic antibodies in the lung and protects against virus challenge in …
JR Francica, BJ Flynn, KE Foulds, AT Noe, AP Werner… - BioRxiv, 2021 - ncbi.nlm.nih.gov
Adjuvanted soluble protein vaccines have been used extensively in humans for protection
against various viral infections based on their robust induction of antibody responses. Here …
against various viral infections based on their robust induction of antibody responses. Here …
Humoral responses against SARS-CoV-2 and variants of concern after mRNA vaccines in patients with non-Hodgkin lymphoma and chronic lymphocytic leukemia
PURPOSE Patients with non-Hodgkin lymphoma including chronic lymphocytic leukemia
(NHL/CLL) are at higher risk of severe SARS-CoV-2 infection. We investigated vaccine …
(NHL/CLL) are at higher risk of severe SARS-CoV-2 infection. We investigated vaccine …
[HTML][HTML] An mRNA vaccine encoding the SARS-CoV-2 receptor-binding domain protects mice from various Omicron variants
R Uraki, M Imai, M Ito, S Yamayoshi, M Kiso, N Jounai… - npj Vaccines, 2024 - nature.com
Here, we assessed the efficacy of a lipid nanoparticle-based mRNA vaccine candidate
encoding the receptor-binding domain (LNP-mRNA-RBD) in mice. Mice immunized with …
encoding the receptor-binding domain (LNP-mRNA-RBD) in mice. Mice immunized with …
[HTML][HTML] SARS-CoV-2 shedding and evolution in immunocompromised hosts during the Omicron period: a multicenter prospective analysis
Background: Prolonged SARS-CoV-2 infections in immunocompromised hosts may predict
or source the emergence of highly mutated variants. The types of immunosuppression …
or source the emergence of highly mutated variants. The types of immunosuppression …
Reduced binding and neutralization of infection-and vaccine-induced antibodies to the B. 1.351 (South African) SARS-CoV-2 variant
VV Edara, C Norwood, K Floyd, L Lai… - BioRxiv, 2021 - biorxiv.org
The emergence of SARS-CoV-2 variants with mutations in the spike protein is raising
concerns about the efficacy of infection-or vaccine-induced antibodies to neutralize these …
concerns about the efficacy of infection-or vaccine-induced antibodies to neutralize these …
The serological sciences network (SeroNet) for COVID-19: depth and breadth of serology assays and plans for assay harmonization
ABSTRACT In October 2020, the National Cancer Institute (NCI) Serological Sciences
Network (SeroNet) was established to study the immune response to COVID-19, and “to …
Network (SeroNet) was established to study the immune response to COVID-19, and “to …
An inactivated NDV-HXP-S COVID-19 vaccine elicits a higher proportion of neutralizing antibodies in humans than mRNA vaccination
JM Carreño, A Raskin, G Singh, J Tcheou… - Science Translational …, 2023 - science.org
NDV-HXP-S is a recombinant Newcastle disease virus–based vaccine against SARS-CoV-
2, which expresses an optimized (HexaPro) spike protein on its surface. The vaccine can be …
2, which expresses an optimized (HexaPro) spike protein on its surface. The vaccine can be …
[HTML][HTML] Neutralizing antibody: a savior in the Covid-19 disease
SL Gupta, RK Jaiswal - Molecular biology reports, 2022 - Springer
Coronavirus outbreak was declared a pandemic by World Health Organization (WHO) in
March 2020. The pandemic has led to a devastating loss of life. It has shown us how …
March 2020. The pandemic has led to a devastating loss of life. It has shown us how …