Pharmacology, particle deposition and drug administration techniques of intranasal corticosteroids for treating allergic rhinitis
C Rollema, EN van Roon… - Clinical & …, 2022 - Wiley Online Library
This review presents an overview of the available literature regarding intranasal
corticosteroids (INCs) for the treatment of allergic rhinitis (AR). Various treatment options …
corticosteroids (INCs) for the treatment of allergic rhinitis (AR). Various treatment options …
An idealized geometry that mimics average nasal spray deposition in adults: A computational study
This work describes the development of an idealized geometry that mimics average regional
deposition of nasal sprays within realistic adult nasal geometries. Previous simulation …
deposition of nasal sprays within realistic adult nasal geometries. Previous simulation …
Validation and Sensitivity analysis for a nasal spray deposition computational model
Validating numerical models against experimental models of nasal spray deposition is
challenging since many aspects must be considered. That being said, it is a critical step in …
challenging since many aspects must be considered. That being said, it is a critical step in …
From SARS-CoV-2 infection to COVID-19 morbidity: an in silico projection of virion flow rates to the lower airway via nasopharyngeal fluid boluses
Background: While the nasopharynx is initially the dominant upper airway infection site for
SARS-CoV-2, the physiologic mechanism launching the infection at the lower airway is still …
SARS-CoV-2, the physiologic mechanism launching the infection at the lower airway is still …
Anatomically realistic nasal replicas capturing the range of nasal spray drug delivery in adults
To improve the relationships between commonly conducted in vitro studies for locally-acting
nasal spray drug products with in vivo regional deposition, this study developed a set of in …
nasal spray drug products with in vivo regional deposition, this study developed a set of in …
[PDF][PDF] Exposure to a COVID-19 carrier: transmission trends in respiratory tract and estimation of infectious dose
S Basu - medRxiv, 2020 - scholar.archive.org
How human respiratory physiology and inhaled airflow therein proceed to impact
transmission of SARS-CoV-2, leading to the initial infection, is an open question. An answer …
transmission of SARS-CoV-2, leading to the initial infection, is an open question. An answer …
Characterizing regional drug delivery within the nasal airways
Introduction The nose has been receiving increased attention as a route for drug delivery. As
the site of deposition constitutes the first point of contact of the body with the drug …
the site of deposition constitutes the first point of contact of the body with the drug …
Mechanistic Formulation Design of Spray-Dried Powders
Spray drying is gaining traction in the pharmaceutical industry as one of the processing
methods of choice for the manufacture of solid dosage forms intended for pulmonary, oral …
methods of choice for the manufacture of solid dosage forms intended for pulmonary, oral …
Numerical and machine learning analysis of the parameters affecting the regionally delivered nasal dose of nano-and micro-sized aerosolized drugs
The nasal epithelium is an important target for drug delivery to the nose and secondary
organs such as the brain via the olfactory bulb. For both topical and brain delivery, the …
organs such as the brain via the olfactory bulb. For both topical and brain delivery, the …
Nasal saline irrigation–A review of current anatomical, clinical and computational modelling approaches
H Salati, J Bartley, DE White - Respiratory physiology & neurobiology, 2020 - Elsevier
Nasal saline irrigation is frequently utilised in allergic rhinitis and rhinosinusitis
management, and after nasal and sinus surgery. Anatomical modelling, clinical and …
management, and after nasal and sinus surgery. Anatomical modelling, clinical and …