Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …

Epigenetic dysregulation emerges as a critical hallmark and driving force of aging. Although
still an evolving field with much to explore, it has rapidly gained significance by providing …

Ageing is a critical factor in spinal-cord-associated disorders, yet the ageing-specific
mechanisms underlying this relationship remain poorly understood. Here, to address this …

Liver disease has become one of the main causes of health issue worldwide. Sirtuin (Sirt) 2
is a nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase, and is expressed in …

Cardiac aging is a multifaceted process that encompasses structural and functional
alterations culminating in heart failure. As the elderly population continues to expand, there …

Fibrosis, which is primarily marked by excessive extracellular matrix (ECM) deposition, is a
pathophysiological process associated with many disorders, which ultimately leads to organ …

Simple Summary In the last decades there has been a demographic growth of the elderly
population, a trend that will continue due to the increase in life expectancy. Hence …

This study aims to enhance the prognosis prediction of Head and Neck Squamous Cell
Carcinoma (HNSCC) by employing artificial intelligence (AI) to analyse CDKN2A gene …

Age is a prominent risk factor for cardiometabolic disease, and often leads to heart structural
and functional changes. However, precise molecular mechanisms underlying cardiac …

As the global aging population continues to expand, the impact of age-related
cardiovascular diseases (CVDs) on health and longevity has garnered increasing concern …