Hypoxia is implicated in many aspects of tumor development, angiogenesis, and growth in
many different tumors. Brain tumors, particularly the highly aggressive glioblastoma …

Glioblastoma multiforme (GBM, WHO grade IV) is the most common and lethal subtype of
primary brain tumor with a median overall survival of 15 months from the time of diagnosis …

We report pronounced and specific antiglioblastoma cell phototoxicity of 5 nm TiO2 particles
covalently tethered to an antibody via a dihydroxybenzene bivalent linker. The linker …

Background and purpose Grading of cerebral gliomas is important both in treatment
decision and assessment of prognosis. The purpose of this study was to determine the …

Background Extent of tumor resection (EOTR) in glioblastoma surgery plays an important
role in improving survival. Objective To analyze the efficacy, safety and reliability of fluid …

Programmed death ligand 1 (PD-L1) plays a key role in glioblastoma multiforme (GBM)
immunosuppression, vitality, proliferation, and migration, and is therefore a promising target …

Primary brain and CNS tumor incidence is approximately 19 per 100,000 individuals per
year in the United States compared with seven per 100,000 individuals worldwide. 1, 2 …

In recent clinical observation, the growth of endothelial tumors, such as hemangiomas of
infancy, was repressed by the non-selective β-adrenergic antagonist propranolol possibly …

Abstract Chitinase 3–like 1 (Chi3l1) is a secreted protein that is highly expressed in
glioblastoma. Here, we show that Chi3l1 alters the state of glioma stem cells (GSC) to …

Gliomas, the most common primary brain tumors, are diffusive and highly invasive. The
standard treatment for brain tumors consists of a combination of surgery, radiation therapy …